PNKD and ENO3

Number of citations of the paper that reports this interaction (PubMedID 15188056)
0

Data Source:
HPRD (two hybrid, in vitro)

		PNKD	ENO3
Description		PNKD metallo-beta-lactamase domain containing	enolase 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Membrane Presynaptic Cytosol	Phosphopyruvate Hydratase Complex Extracellular Space Cytoplasm Cytosol Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Hydroxyacylglutathione Hydrolase Activity Protein Binding Hydrolase Activity Metal Ion Binding	Magnesium Ion Binding Phosphopyruvate Hydratase Activity Protein Binding Lyase Activity Metal Ion Binding
	Biological Process	Methylglyoxal Catabolic Process To D-lactate Via S-lactoyl-glutathione Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Dopamine Metabolic Process Negative Regulation Of Neurotransmitter Secretion Neuromuscular Process Controlling Posture	Gluconeogenesis Glycolytic Process Canonical Glycolysis
Pathways			Glycolysis Gluconeogenesis
Drugs			2-phospho-D-glyceric acid Phosphoenolpyruvate 2-Phosphoglycolic Acid Phosphonoacetohydroxamic Acid
Diseases		Primary torsion dystonia (PTD)
GWAS		Appendicular lean mass ( 33097823) Colorectal cancer ( 28960316) Colorectal cancer or advanced adenoma ( 30510241) Glycated hemoglobin levels ( 34059833) Granulocyte count ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 23128233 28067908) Liver enzyme levels (alkaline phosphatase) ( 33972514) Monocyte count ( 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Plateletcrit ( 32888494 27863252) Red cell distribution width ( 28957414 32888494 27863252) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30578418) Triglyceride levels ( 32203549) White blood cell count ( 27863252)	Keratoconus ( 33649486) Red cell distribution width ( 32888494)
Interacting Genes		7 interacting genes: APP ENO3 KCTD9 KLHL20 MAGEA11 MYL12B UBC	20 interacting genes: ALDOA APP DCTN1 DSP HSPB2 KALRN LINC01554 MAN2A2 MTMR14 NEB PGM1 PKM PNKD SGCG SNAPIN SPTB TCAP TRAPPC2 TRIM63 TTN
Entrez ID		25953	2027
HPRD ID		11369	11746
Ensembl ID		ENSG00000127838	ENSG00000108515
Uniprot IDs		Q8N490	P13929
PDB IDs			2XSX
Enriched GO Terms of Interacting Partners?			M Band I Band Titin-telethonin Complex Skeletal Muscle Myosin Thick Filament Assembly Sarcomerogenesis Cytoplasm Somatic Muscle Development Myosin Filament Assembly Actin Cytoskeleton Supramolecular Fiber Organization Z Disc Structural Constituent Of Muscle Skeletal Muscle Thin Filament Assembly Glycolytic Process ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Detection Of Muscle Stretch Hexose Metabolic Process Ribonucleoside Diphosphate Catabolic Process ADP Metabolic Process Nucleoside Diphosphate Catabolic Process Cardiac Muscle Tissue Morphogenesis Monosaccharide Metabolic Process Pyruvate Metabolic Process Muscle Contraction Muscle Tissue Morphogenesis Ribonucleoside Diphosphate Metabolic Process Neuron Projection Maintenance Contractile Muscle Fiber Titin Binding Purine Ribonucleotide Catabolic Process Axo-dendritic Transport Striated Muscle Contraction Nucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process System Process Cardiac Myofibril Assembly Muscle Filament Sliding Actin-myosin Filament Sliding Muscle System Process Actin Filament Organization Nucleotide Catabolic Process Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Cardiac Muscle Hypertrophy Ficolin-1-rich Granule Lumen Response To Muscle Stretch Nucleoside Phosphate Catabolic Process Cytosol Muscle Hypertrophy
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?