RPL36 and NR2C2

		RPL36	NR2C2
Description		ribosomal protein L36	nuclear receptor subfamily 2 group C member 2
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GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Ribosome Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cytoplasmic Translation Translation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Spermatogenesis Nervous System Development Cell Differentiation Intracellular Receptor Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JNK Cascade
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS			Alcohol and nicotine co-dependence ( 22488850) Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		4 interacting genes: APP DUX4 PTEN RPL18A	23 interacting genes: AR CD2AP CDC37 CHUK ESR1 FKBP5 HDAC4 HNF4A HSP90AA1 HSP90AB1 IKBKB ITSN2 JAZF1 KDM1A NR2C1 NR2C2AP PEBP1 RAC1 RXRB TAB1 TAB2 TRAF2 TRIM55
Entrez ID		25873	7182
HPRD ID		10201	03253
Ensembl ID		ENSG00000130255	ENSG00000177463
Uniprot IDs		Q9Y3U8	F2YGU2 P49116
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7QGG 7QVP 7XNX 7XNY 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO	3P0U 7XV6 7XV8 7XV9 7XVA
Enriched GO Terms of Interacting Partners?		Ruffle Membrane Negative Regulation Of Cell Population Proliferation Cell Projection Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Neuron Projection Organization Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Reproductive Process Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of RNA Metabolic Process Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Nucleobase-containing Compound Metabolic Process Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Modulation Of Excitatory Postsynaptic Potential Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Reproductive Behavior Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Macropinocytosis Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Early Phagosome Membrane Cold Acclimation	Regulation Of Signal Transduction Non-canonical NF-kappaB Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Intracellular Signal Transduction Nuclear Receptor Activity Regulation Of Signaling Canonical NF-kappaB Signal Transduction Intracellular Receptor Signaling Pathway Nuclear Steroid Receptor Activity Intracellular Signaling Cassette Nitric-oxide Synthase Regulator Activity CD40 Receptor Complex Positive Regulation Of Intracellular Signal Transduction Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Protein Modification Process HSP90-CDC37 Chaperone Complex Regulation Of Nitric Oxide Metabolic Process Protein Kinase Binding Scaffold Protein Binding Positive Regulation Of Signal Transduction Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway IkappaB Kinase Activity Rho GDP-dissociation Inhibitor Binding Protein-containing Complex Positive Regulation Of Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Nuclear Receptor-mediated Signaling Pathway Protein Folding Chaperone Complex Cytosol Enzyme Binding Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Nitric Oxide Biosynthetic Process Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Metabolic Process Cytoplasm Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Innate Immune Response Telomerase Holoenzyme Complex Assembly Regulation Of Immune Response Histone Deacetylase Binding Nucleoplasm Response To External Biotic Stimulus IkappaB Kinase Complex Hormone-mediated Signaling Pathway Dendritic Growth Cone TPR Domain Binding
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