TPSG1 and HPCAL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPSG1	HPCAL1
Description		tryptase gamma 1	hippocalcin like 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane	Membrane
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Proteolysis	Regulation Of Signal Transduction
Pathways
Drugs
Diseases
GWAS			Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease ( 34020725) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Femur bone mineral density x serum urate levels interaction ( 34046847) Kidney function decline traits ( 25493955) Lung function (FEV1/FVC) ( 30061609) Platelet distribution width ( 32888494)
Interacting Genes		2 interacting genes: HPCAL1 NCALD	39 interacting genes: AMOT ATXN1 C19orf44 C1QTNF2 CA3 CEBPA COLGALT2 CREM DTX2 EFEMP2 EPHB3 FZD7 GATA5 HMG20A IKBKG KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP4-2 KRTAP5-9 LITAF MDFI MICOS10-NBL1 MYDGF NBL1 NBPF19 NOTCH2NLA PLAAT2 SERPINI2 SLC34A1 TPSG1 VWC2 ZNF655
Entrez ID		25823	3241
HPRD ID		07160	02564
Ensembl ID		ENSG00000116176	ENSG00000115756
Uniprot IDs		Q9NRR2	O75544 P37235 Q6FGY1
PDB IDs			5T7C
Enriched GO Terms of Interacting Partners?		Calcium Ion Binding Clathrin Coat Of Trans-Golgi Network Vesicle Alpha-tubulin Binding Regulation Of Systemic Arterial Blood Pressure Clathrin Binding Tubulin Binding	Intermediate Filament Keratin Filament Identical Protein Binding Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Determination Of Dorsal Identity Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction Maintenance Of Protein Location Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Developmental Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?