HPCAL1 and SLC34A1

Number of citations of the paper that reports this interaction (PMID 14694264)
2

Data Source:
HPRD (two hybrid)

		HPCAL1	SLC34A1
Gene Name		hippocalcin-like 1	solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Vesicular Exosome	Endosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Apical Plasma Membrane Brush Border Membrane Membrane-bounded Vesicle Membrane Raft Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding	Protein Binding Symporter Activity Sodium-dependent Phosphate Transmembrane Transporter Activity PDZ Domain Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	Signal Transduction	Ossification Kidney Development Ion Transport Sodium Ion Transport Phosphate Ion Transport Glycoprotein Metabolic Process Response To Lead Ion Response To Magnesium Ion Response To Estradiol Response To Vitamin A Response To Potassium Ion Indole Metabolic Process Response To Drug Sodium-dependent Phosphate Transport Positive Regulation Of Membrane Potential Response To Cadmium Ion Response To Mercury Ion Bone Remodeling Protein Homooligomerization Phosphate Ion Homeostasis Transmembrane Transport Response To Growth Hormone Cellular Response To Metal Ion Cellular Response To Parathyroid Hormone Stimulus Tricarboxylic Acid Metabolic Process Cellular Response To Staurosporine Response To Thyroid Hormone Dentinogenesis Gentamycin Metabolic Process Arsenate Ion Transmembrane Transport Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport
Pathways			Sodium-coupled phosphate cotransporters Type II Na+/Pi cotransporters Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881) Chronic kidney disease ( 20383146) Nephrolithiasis ( 22396660)
Protein-Protein Interactions		15 interactors: ATXN1 C1QTNF2 DTX2 HMG20A IKBKG KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 NOTCH2NL SLC34A1	10 interactors: BSPRY FHL2 HPCAL1 HSP90AA1 HSP90AB1 MAST2 PEX19 SLC9A3R1 SLC9A3R2 YIF1A
Entrez ID		3241	6569
HPRD ID		02564	08918
Ensembl ID		ENSG00000115756	ENSG00000131183
Uniprot IDs		O75544 P37235 Q6FGY1	Q06495 Q7Z725 Q86VN6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Sodium-dependent Phosphate Transport Positive Regulation Of Phosphate Transmembrane Transport Gentamycin Metabolic Process Indole Metabolic Process Arsenate Ion Transmembrane Transport Cellular Response To Staurosporine Notch Signaling Pathway Activation Of MAPK Activity Regulation Of Sodium-dependent Phosphate Transport Dentinogenesis Regulation Of Phosphate Transport Positive Regulation Of MAP Kinase Activity Cellular Response To Parathyroid Hormone Stimulus Sodium-dependent Phosphate Transport Response To Potassium Ion Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Protein Homooligomerization Activation Of Protein Kinase Activity Regulation Of Membrane Potential Positive Regulation Of Protein Serine/threonine Kinase Activity	Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Response To Unfolded Protein Regulation Of Cellular Response To Heat Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Protein Folding Intracellular Protein Transmembrane Transport Regulation Of Nitric Oxide Biosynthetic Process Protein Transmembrane Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Heat Renal Phosphate Ion Absorption Negative Regulation Of Lipid Binding Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Response To Heat Atrial Cardiac Muscle Cell Development Peroxisome Membrane Biogenesis Protein Import Into Mitochondrial Outer Membrane Regulation Of Reactive Oxygen Species Metabolic Process Protein Import Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Response To Temperature Stimulus Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Protein Kinase Activity Intracellular Receptor Signaling Pathway Protein Import Into Peroxisome Membrane Chaperone-mediated Protein Transport Phospholipase C-activating Dopamine Receptor Signaling Pathway Peroxisomal Membrane Transport Regulation Of Kinase Activity Establishment Of Protein Localization To Membrane Bile Acid Secretion Peroxisome Fission Oligopeptide Transport Regulation Of Binding Phagocytosis Positive Regulation Of Protein Import Into Nucleus, Translocation Negative Regulation Of Sodium Ion Transport Renal Absorption Regulation Of Proton Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Tagcloud ?		alpha4beta2 antioxidative apoe4 b5 calbindin comparatively d28k dendrites exam explaining gwas hint instance limbic mmse nachr ncs neurofibrillary neuroplasticity nft nicotinergic nicotinic psychosis tangles tie vilip visinin vsnl1 vsnls
Tagcloud (Difference) ?		alpha4beta2 antioxidative apoe4 b5 calbindin comparatively d28k dendrites exam explaining gwas hint instance limbic mmse nachr ncs neurofibrillary neuroplasticity nft nicotinergic nicotinic psychosis tangles tie vilip visinin vsnl1 vsnls
Tagcloud (Intersection) ?