HPCAL1

Description		hippocalcin like 1
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GO Annotations	Cellular Component	Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Signal Transduction
Pathways
Drugs
Diseases
GWAS		Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease ( 34020725) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Femur bone mineral density x serum urate levels interaction ( 34046847) Kidney function decline traits ( 25493955) Lung function (FEV1/FVC) ( 30061609) Platelet distribution width ( 32888494)
Interacting Genes		39 interacting genes: AMOT ATXN1 C19orf44 C1QTNF2 CA3 CEBPA COLGALT2 CREM DTX2 EFEMP2 EPHB3 FZD7 GATA5 HMG20A IKBKG KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP17-1 KRTAP4-2 KRTAP5-9 LITAF MDFI MICOS10-NBL1 MYDGF NBL1 NBPF19 NOTCH2NLA PLAAT2 SERPINI2 SLC34A1 TPSG1 VWC2 ZNF655
Entrez ID		3241
HPRD ID		02564
Ensembl ID		ENSG00000115756
Uniprot IDs		O75544 P37235 Q6FGY1
PDB IDs		5T7C
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Identical Protein Binding Sequestering Of BMP In Extracellular Matrix Sequestering Of BMP From Receptor Via BMP Binding Determination Of Dorsal Identity Morphogen Activity Negative Regulation Of Monocyte Chemotaxis Sequestering Of Extracellular Ligand From Receptor Extracellular Negative Regulation Of Signal Transduction Maintenance Of Protein Location Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Developmental Process
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