HYPK and MAGEA1

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid)

		HYPK	MAGEA1
Name		huntingtin interacting protein K	MAGE family member A1
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Protein-containing Complex	Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Protein Folding Chaperone	Protein Binding Histone Deacetylase Binding
	Biological Process	Protein Folding Negative Regulation Of Apoptotic Process Protein Stabilization	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Notch Signaling Pathway
GWAS		No GWAS studies recorded	No GWAS studies recorded
Interacting Genes		31 interacting genes: BOLL C2orf68 CSNK2B CYSRT1 HNRNPF HTT KRTAP12-2 KRTAP19-5 KRTAP3-2 KRTAP3-3 KRTAP8-1 MAGEA1 MAP1LC3B MDFI NAA10 NAA15 NEDD8 PCBP1 PHC3 PRR20A PRR20B PRR20C PRR20D PRR20E RBFOX1 RHOXF2 SP4 TENT5A THAP1 TXLNA VENTX	25 interacting genes: ABI2 CEP57L1 DNM1L HDAC1 HLA-A HLA-B HYPK LRSAM1 MDM4 MIEF1 NOTCH1 PBX3 PCGF6 RAB17 RNF166 S100A9 SELPLG SFN SGK1 SH3GLB2 SHFL SNW1 TRIM31 UQCRB ZNF564
Entrez ID		25764	4100
HPRD ID		13724	02059
Ensembl ID		ENSG00000242028	ENSG00000198681
Uniprot IDs		Q9NX55	P43355
PDB IDs		6C95 6PW9 9F1D	1W72 3BO8
GO Terms Enriched among Interactors		Intermediate Filament NatA Complex N-terminal Protein Amino Acid Acetylation	TAP Binding Compartment Pattern Specification Protection From Natural Killer Cell Mediated Cytotoxicity MHC Class I Protein Complex Detection Of Bacterium Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib Mitochondrial Fission Regulation Of Cellular Component Organization Response To External Biotic Stimulus Epidermal Cell Differentiation Negative Regulation Of Innate Immune Response Negative Regulation Of Myotube Differentiation Innate Immune Response Recycling Endosome Membrane Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Atrioventricular Valve Morphogenesis Endocardial Cushion Morphogenesis Positive Regulation Of Mitochondrial Fission Defense Response Host-mediated Perturbation Of Symbiont Process Notch Binding Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Defense Response To Symbiont Modulation Of Process Of Another Organism Defense Response To Other Organism Response To Other Organism Positive Regulation Of Epidermal Cell Differentiation Host-mediated Perturbation Of Viral Transcription Antigen Processing And Presentation Of Endogenous Antigen Regulation Of Mitochondrial Fission Lumenal Side Of Endoplasmic Reticulum Membrane Autophagy Detection Of Biotic Stimulus Positive Regulation Of Epidermis Development Endoderm Development Regulation Of Viral Process Positive Regulation Of Glial Cell Differentiation Positive Regulation Of T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Binding Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Venous Endothelial Cell Differentiation Coronary Sinus Valve Morphogenesis Foregut Morphogenesis Posterior Compartment Specification Anterior Compartment Pattern Formation S100A9 Complex Viral Process