TEPSIN and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEPSIN	RAB3IP
Description		TEPSIN adaptor related protein complex 4 accessory protein	RAB3A interacting protein
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Membrane Coated Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cytoskeleton Lamellipodium Vesicle Ciliary Basal Body Cell Projection Perinuclear Region Of Cytoplasm Proximal Dendrite
	Molecular Function	Protein Binding Protein-containing Complex Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Identical Protein Binding GTPase Binding
	Biological Process		Protein Targeting To Membrane Golgi To Plasma Membrane Transport Protein Transport Negative Regulation Of Filopodium Assembly Cilium Assembly Ciliary Basal Body-plasma Membrane Docking
Pathways			Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		126 interacting genes: AATK ACBD7 AGRN AIRIM AP1M1 APOL6 APP ASAP3 ASB3 ATOSB BCL2L14 BCL2L15 BIRC7 BPIFA1 BTBD3 C1QTNF4 CBX8 CCDC146 CCNC CDC23 CINP CLCNKA CLIC3 CNTF CPNE7 CSNK2A1 CTAG1A CTAG1B CYSRT1 DEF6 DUSP29 DUSP4 DZIP1L EIF1AD FAM90A1 FARS2 FKBP6 FLACC1 FNDC3B GNG13 GOLGA2 GPANK1 GPRASP3 GRB10 GRIPAP1 GUCD1 HAT1 HCK HPCA HSF2BP HSPB7 IL16 IQGAP1 KCTD6 KCTD9 KHNYN KLHL38 KRT31 KRT34 KRT35 KRTAP6-2 LENG1 LGALS14 LMO3 LSM3 LYG2 MAT2B MED18 MFAP1 MLX MORF4L1 MSGN1 MTUS2 NDOR1 NEK6 NGB NME7 NR2C2AP NTAQ1 NUDT14 NUDT21 OAZ3 OR6B1 PAX9 PCDHB3 PLEKHA2 PSMA6 RAB3IP RAD51D RANBP3 RNF135 SEC14L4 SLU7 SNRNP25 SORBS2 SORBS3 SZT2 TAPBPL TBC1D13 TBC1D22B TCEA2 TCL1A TFAP2D THRSP TRAPPC2 TRAPPC2B TRAPPC6A TRIM23 TRIM45 TRIM50 TRIM54 TRIM68 TSEN15 TSEN2 TSHZ3 TSSK3 UBASH3B UTP23 VPS26C WDR25 YPEL3 ZIC1 ZMYND12 ZNF343 ZNF629 ZRSR2	32 interacting genes: BANP CCDC196 CHCHD3 DNAJB13 FAM124A KRT40 MB21D2 MBD3 MVP NAA10 PEG10 PKN1 PLOD3 PPL PRKAB2 RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TBC1D21 TEPSIN TRAPPC6A TXNDC5 ZBTB16 ZNF410 ZNF76
Entrez ID		146705	117177
HPRD ID		08103	10565
Ensembl ID		ENSG00000167302	ENSG00000127328
Uniprot IDs		A0A1B0GV70 Q96N21	Q96QF0
PDB IDs		5WF9 5WFB	4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Identical Protein Binding TRAPPIII Protein Complex	Myosin V Binding Protein Transport Synaptic Vesicle Regulation Of Neuronal Synaptic Plasticity Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Neurotransmitter Receptor Transport To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane Exocytosis Plasma Membrane To Endosome Transport Intracellular Protein Localization Vesicle Organization GTPase Activity Vesicle-mediated Transport Endosome To Plasma Membrane Protein Transport Neurotransmitter Receptor Transport Endocytic Recycling Trans-Golgi Network Transport Vesicle Endosome Establishment Of Protein Localization Phagocytic Vesicle GTP Binding Vesicle-mediated Transport In Synapse GTP-dependent Protein Binding Secretion By Cell Cytoplasmic Vesicle Recycling Endosome Membrane Extracellular Exosome Regulation Of Long-term Neuronal Synaptic Plasticity Trans-Golgi Network Membrane Organelle Organization Glycerol-3-phosphate Dehydrogenase (quinone) Activity Protein Localization To Postsynapse Protein Localization To Postsynaptic Membrane Endosomal Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Synaptic Vesicle Endosomal Processing Coated Vesicle Membrane Organelle Fusion
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