TEPSIN and KHNYN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TEPSIN	KHNYN
Description		TEPSIN adaptor related protein complex 4 accessory protein	KH and NYN domain containing
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Membrane Coated Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane	Cellular_component Nucleus Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding Protein-containing Complex Binding	Molecular_function RNA Binding MRNA Binding RNA Endonuclease Activity Protein Binding
	Biological Process		Biological_process
Pathways
Drugs
Diseases
GWAS		IgG N-glycosylation phenotypes (multivariate analysis) ( 32128391)	Appendicular lean mass ( 33097823)
Interacting Genes		126 interacting genes: AATK ACBD7 AGRN AIRIM AP1M1 APOL6 APP ASAP3 ASB3 ATOSB BCL2L14 BCL2L15 BIRC7 BPIFA1 BTBD3 C1QTNF4 CBX8 CCDC146 CCNC CDC23 CINP CLCNKA CLIC3 CNTF CPNE7 CSNK2A1 CTAG1A CTAG1B CYSRT1 DEF6 DUSP29 DUSP4 DZIP1L EIF1AD FAM90A1 FARS2 FKBP6 FLACC1 FNDC3B GNG13 GOLGA2 GPANK1 GPRASP3 GRB10 GRIPAP1 GUCD1 HAT1 HCK HPCA HSF2BP HSPB7 IL16 IQGAP1 KCTD6 KCTD9 KHNYN KLHL38 KRT31 KRT34 KRT35 KRTAP6-2 LENG1 LGALS14 LMO3 LSM3 LYG2 MAT2B MED18 MFAP1 MLX MORF4L1 MSGN1 MTUS2 NDOR1 NEK6 NGB NME7 NR2C2AP NTAQ1 NUDT14 NUDT21 OAZ3 OR6B1 PAX9 PCDHB3 PLEKHA2 PSMA6 RAB3IP RAD51D RANBP3 RNF135 SEC14L4 SLU7 SNRNP25 SORBS2 SORBS3 SZT2 TAPBPL TBC1D13 TBC1D22B TCEA2 TCL1A TFAP2D THRSP TRAPPC2 TRAPPC2B TRAPPC6A TRIM23 TRIM45 TRIM50 TRIM54 TRIM68 TSEN15 TSEN2 TSHZ3 TSSK3 UBASH3B UTP23 VPS26C WDR25 YPEL3 ZIC1 ZMYND12 ZNF343 ZNF629 ZRSR2	5 interacting genes: CUL1 CUL2 PLOD3 TEPSIN UBC
Entrez ID		146705	23351
HPRD ID		08103	11076
Ensembl ID		ENSG00000167302	ENSG00000100441
Uniprot IDs		A0A1B0GV70 Q96N21	A8K6L5 O15037
PDB IDs		5WF9 5WFB	2N5M 2N7K 8WZC 9BGL 9CS9 9HTS
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Identical Protein Binding TRAPPIII Protein Complex	Ubiquitin Ligase Complex Scaffold Activity Modification-dependent Protein Catabolic Process Cullin-RING Ubiquitin Ligase Complex Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Modification Process Post-translational Protein Modification Ubiquitin Protein Ligase Binding Macromolecule Catabolic Process SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process SCF Ubiquitin Ligase Complex Proteolysis Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Coated Vesicle Membrane Ubiquitin-dependent Protein Catabolic Process Hydroxylysine Biosynthetic Process Protein Metabolic Process Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Procollagen Glucosyltransferase Activity Procollagen-lysine 5-dioxygenase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Basement Membrane Assembly Procollagen Galactosyltransferase Activity Intrinsic Apoptotic Signaling Pathway Catabolic Process Epidermis Morphogenesis Protein-macromolecule Adaptor Activity Peptidyl-lysine Hydroxylation Ubiquitin-protein Transferase Activity Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Endothelial Cell Morphogenesis Apoptotic Signaling Pathway Protein Tag Activity Protein Hydroxylation Cul2-RING Ubiquitin Ligase Complex L-ascorbic Acid Binding Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Epithelial Cell Apoptotic Process Macromolecule Metabolic Process Small Molecule Binding Heart Valve Development
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