GABRB1 and C1QBP

Number of citations of the paper that reports this interaction (PMID 11350968)
2

Data Source:
HPRD (two hybrid)

		GABRB1	C1QBP
Gene Name		gamma-aminobutyric acid (GABA) A receptor, beta 1	complement component 1, q subcomponent binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane GABA-A Receptor Complex	Extracellular Space Nucleus Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane Cell Surface Membrane
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Ligand-gated Ion Channel Activity	Complement Component C1q Binding Transcription Corepressor Activity MRNA Binding Protein Kinase C Binding Protein Binding Hyaluronic Acid Binding Transcription Factor Binding Kininogen Binding Adrenergic Receptor Binding Mitochondrial Ribosome Binding
	Biological Process	Transport Ion Transport Signal Transduction Synaptic Transmission Ion Transmembrane Transport Transmembrane Transport Cellular Response To Histamine Chloride Transmembrane Transport	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated MRNA Processing Apoptotic Process Immune Response Complement Activation, Classical Pathway Blood Coagulation Blood Coagulation, Intrinsic Pathway RNA Splicing Phosphatidylinositol 3-kinase Signaling Viral Process Regulation Of Complement Activation Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-12 Production Negative Regulation Of MDA-5 Signaling Pathway Negative Regulation Of RIG-I Signaling Pathway Mature Ribosome Assembly Positive Regulation Of Apoptotic Process Innate Immune Response Positive Regulation Of Cell Adhesion Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Defense Response To Virus Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Mitochondrial Translation Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Trophoblast Cell Migration Positive Regulation Of Dendritic Cell Chemotaxis
Pathways		GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses	Intrinsic Pathway Formation of Fibrin Clot (Clotting Cascade)
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: AKAP5 ARFGEF2 C1QBP NEUROD4 NOD1 PIK3CA UBQLN1	24 interactors: C1QA CEBPA COIL EXOSC6 GAB1 GABRB1 HABP4 HNRNPD HRK MAPK1 MAPK3 MMP14 NFKBIE NFYB PRKCA PRKCD PRKCZ PRKD1 PRRC2A SRSF1 SRSF9 TOP3B YWHAB YWHAG
Entrez ID		2560	708
HPRD ID		15924	03168
Ensembl ID		ENSG00000163288	ENSG00000108561
Uniprot IDs		P18505	Q07021
PDB IDs			1P32 3RPX
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Cellular Response To Stimulus Interleukin-8 Biosynthetic Process Regulation Of Metabolic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Signal Transduction Regulation Of Cytokine Production Regulation Of Apoptotic Process Regulation Of Cell Death Hypomethylation Of CpG Island Positive Regulation Of Trophoblast Cell Migration Negative Regulation Of MDA-5 Signaling Pathway Response To Stimulus Positive Regulation Of Immune Response Regulation Of Signaling Signal Transduction Phosphatidylinositol-mediated Signaling Positive Regulation Of Metabolic Process Signaling Intracellular Signal Transduction Interleukin-8 Production Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Cell Communication Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Regulation Of Cellular Protein Metabolic Process Amacrine Cell Differentiation Positive Regulation Of Protein Kinase A Signaling Regulation Of Immune Response Positive Regulation Of Mitochondrial Translation Regulation Of Genetic Imprinting Positive Regulation Of Immune System Process Positive Regulation Of Dendritic Cell Chemotaxis Regulation Of Protein Metabolic Process Mature Ribosome Assembly Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of RIG-I Signaling Pathway Regulation Of Mitochondrial Translation Negative Regulation Of Viral-induced Cytoplasmic Pattern Recognition Receptor Signaling Pathway Receptor Recycling Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of RIG-I Signaling Pathway Positive Regulation Of Signal Transduction Negative Regulation Of Anoikis Positive Regulation Of Cytokine Production Blood Coagulation, Intrinsic Pathway	Vascular Endothelial Growth Factor Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Cellular Protein Metabolic Process Platelet Activation Response To Fibroblast Growth Factor Cellular Response To Insulin Stimulus Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Neurotrophin Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Protein Metabolic Process Defense Response Cellular Response To Organonitrogen Compound Regulation Of Protein Kinase Activity Response To Insulin Insulin Receptor Signaling Pathway Regulation Of Protein Phosphorylation Cellular Response To Organic Substance Cellular Response To Peptide Hormone Stimulus Regulation Of Kinase Activity Cellular Response To Peptide Innate Immune Response Response To Organonitrogen Compound Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of MAPK Cascade Immune Response Regulation Of Phosphorylation Response To Hormone Regulation Of Cellular Amino Acid Metabolic Process Apoptotic Process Cell Activation Blood Coagulation Programmed Cell Death Hemostasis Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Response To Peptide Hormone Cell Death Death Regulation Of Phosphorus Metabolic Process
Tagcloud ?		atp5d bear behaviors build cessation chronically clustering diethylamide drd2 hyperactivity illnesses krox20 lsd lysergic medial mpfc ndufa1 neurogenetic neuropeptide neurotransmission npy persist prefrontal qpcr schizophrenia seq sucrose underlie validate	133a a2m affymetrix afzelii borrelia burgdorferii burgeforii c1s cd46 cd59 cfb cfh complement cultivation defence differentiates diploid fhl1 garinii genospecies hgu launch penetrating sensu spirochaete spirochaetes stricto transcriptomes vsig4
Tagcloud (Difference) ?		atp5d bear behaviors build cessation chronically clustering diethylamide drd2 hyperactivity illnesses krox20 lsd lysergic medial mpfc ndufa1 neurogenetic neuropeptide neurotransmission npy persist prefrontal qpcr schizophrenia seq sucrose underlie validate	133a a2m affymetrix afzelii borrelia burgdorferii burgeforii c1s cd46 cd59 cfb cfh complement cultivation defence differentiates diploid fhl1 garinii genospecies hgu launch penetrating sensu spirochaete spirochaetes stricto transcriptomes vsig4
Tagcloud (Intersection) ?