GABRB1

Gene Name		gamma-aminobutyric acid (GABA) A receptor, beta 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Chloride Channel Complex Postsynaptic Membrane GABA-A Receptor Complex
	Molecular Function	GABA-A Receptor Activity Extracellular Ligand-gated Ion Channel Activity Chloride Channel Activity Ligand-gated Ion Channel Activity
	Biological Process	Transport Ion Transport Signal Transduction Synaptic Transmission Ion Transmembrane Transport Transmembrane Transport Cellular Response To Histamine Chloride Transmembrane Transport
Pathways		GABA receptor activation Ion channel transport GABA A receptor activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ligand-gated ion channel transport Orphan transporters Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		7 interactors: AKAP5 ARFGEF2 C1QBP NEUROD4 NOD1 PIK3CA UBQLN1
Entrez ID		2560
HPRD ID		15924
Ensembl ID		ENSG00000163288
Uniprot IDs		P18505
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Intracellular Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Cellular Response To Stimulus Interleukin-8 Biosynthetic Process Regulation Of Metabolic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Signal Transduction Regulation Of Cytokine Production Regulation Of Apoptotic Process Regulation Of Cell Death Hypomethylation Of CpG Island Positive Regulation Of Trophoblast Cell Migration Negative Regulation Of MDA-5 Signaling Pathway Response To Stimulus Positive Regulation Of Immune Response Regulation Of Signaling Signal Transduction Phosphatidylinositol-mediated Signaling Positive Regulation Of Metabolic Process Signaling Intracellular Signal Transduction Interleukin-8 Production Insulin Receptor Signaling Pathway Via Phosphatidylinositol 3-kinase Cell Communication Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Regulation Of Cellular Protein Metabolic Process Amacrine Cell Differentiation Positive Regulation Of Protein Kinase A Signaling Regulation Of Immune Response Positive Regulation Of Mitochondrial Translation Regulation Of Genetic Imprinting Positive Regulation Of Immune System Process Positive Regulation Of Dendritic Cell Chemotaxis Regulation Of Protein Metabolic Process Mature Ribosome Assembly Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Negative Regulation Of RIG-I Signaling Pathway Regulation Of Mitochondrial Translation Negative Regulation Of Viral-induced Cytoplasmic Pattern Recognition Receptor Signaling Pathway Receptor Recycling Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of RIG-I Signaling Pathway Positive Regulation Of Signal Transduction Negative Regulation Of Anoikis Positive Regulation Of Cytokine Production Blood Coagulation, Intrinsic Pathway
Tagcloud ?		atp5d bear behaviors build cessation chronically clustering diethylamide drd2 hyperactivity illnesses krox20 lsd lysergic medial mpfc ndufa1 neurogenetic neuropeptide neurotransmission npy persist prefrontal qpcr schizophrenia seq sucrose underlie validate