MORN5 and AGXT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MORN5	AGXT
Description		MORN repeat containing 5	alanine--glyoxylate aminotransferase
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	Cytoplasm Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Protein Binding	L-serine-pyruvate Transaminase Activity Protein Binding Alanine-glyoxylate Transaminase Activity Transaminase Activity Amino Acid Binding Transferase Activity Pyridoxal Phosphate Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process		L-serine Metabolic Process Notch Signaling Pathway Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-cysteine Catabolic Process L-alanine Catabolic Process Glyoxylate Metabolic Process Oxalic Acid Secretion
Pathways			Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs			Pyridoxal phosphate Serine Glycine Alanine Aminooxyacetic acid N(6)-(pyridoxal phosphate)-L-lysine 4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID
Diseases			Primary hyperoxaluria (HP)
GWAS		Malaria ( 31844061)	Height ( 25282103 31562340) Urinary metabolites ( 26352407)
Interacting Genes		9 interacting genes: AGXT ENKD1 GAS2L2 HAT1 MISP POM121 STAMBPL1 TLX3 USP2	39 interacting genes: ACAT1 ACTMAP ATXN1L BATF3 CFAP68 CHIC2 CYSRT1 EFS FAM168B FHL5 FNTB FOSB GLP1R HOXA1 KRT31 KRT34 KRT37 KRT40 KRTAP1-1 KRTAP12-3 KRTAP3-1 KRTAP6-3 KRTAP8-1 KRTAP9-2 LPXN MDFI MORN5 NBPF19 NOTCH2NLA OIP5 PEX5 PLA2G10 PRDM6 PRICKLE4 RFX6 SNCAIP SPRYD7 TRAPPC14 TTC19
Entrez ID		254956	189
HPRD ID		12947	05048
Ensembl ID		ENSG00000185681	ENSG00000172482
Uniprot IDs		A0A0A0MTF6 Q5VZ52	P21549
PDB IDs			1H0C 1J04 2YOB 3R9A 4CBR 4CBS 4I8A 4KXK 4KYO 5F9S 5HHY 5LUC 5OFY 5OG0 6RV0 6RV1 7NS7
Enriched GO Terms of Interacting Partners?		Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Orientation L-serine-pyruvate Transaminase Activity Establishment Of Spindle Localization Spindle Localization Glycine Biosynthetic Process, By Transamination Of Glyoxylate Glyoxylate Catabolic Process Alanine-glyoxylate Transaminase Activity Oxalic Acid Secretion Protein Deubiquitination Protein Modification By Small Protein Removal Microtubule Cytoskeleton Organization Actin Filament Mitotic Spindle Astral Microtubule End Protein Localization To Microtubule Plus-end Glycine Biosynthetic Process L-alanine Catabolic Process L-alanine Metabolic Process L-cysteine Catabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Negative Regulation Of B Cell Receptor Signaling Pathway
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