MORN5 and HAT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MORN5	HAT1
Description		MORN repeat containing 5	histone acetyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Motile Cilium Sperm Flagellum Cell Projection	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrion Nuclear Matrix Protein-containing Complex
	Molecular Function	Protein Binding	Histone Acetyltransferase Activity Protein Binding Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone Binding Histone H4K12 Acetyltransferase Activity Protein-lysine-acetyltransferase Activity
	Biological Process		Chromatin Organization Nucleosome Assembly Internal Protein Amino Acid Acetylation Subtelomeric Heterochromatin Formation Chromosome Organization
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Malaria ( 31844061)	Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Myopia ( 27182965) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		9 interacting genes: AGXT ENKD1 GAS2L2 HAT1 MISP POM121 STAMBPL1 TLX3 USP2	23 interacting genes: ACAA1 CEBPA EZH2 H2AC20 H3-4 H3C1 H4C14 H4C16 HTR2B KANK4 MEOX2 MORN5 PRKAA2 REL SMAD7 SNAPC1 STEEP1 TCF4 TEPSIN TNFAIP1 TRIB3 YWHAQ ZSCAN4
Entrez ID		254956	8520
HPRD ID		12947	04339
Ensembl ID		ENSG00000185681	ENSG00000128708
Uniprot IDs		A0A0A0MTF6 Q5VZ52	A0AAG2UVM1 O14929
PDB IDs			2P0W 6VO5 9MJG
Enriched GO Terms of Interacting Partners?		Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Orientation L-serine-pyruvate Transaminase Activity Establishment Of Spindle Localization Spindle Localization Glycine Biosynthetic Process, By Transamination Of Glyoxylate Glyoxylate Catabolic Process Alanine-glyoxylate Transaminase Activity Oxalic Acid Secretion Protein Deubiquitination Protein Modification By Small Protein Removal Microtubule Cytoskeleton Organization Actin Filament Mitotic Spindle Astral Microtubule End Protein Localization To Microtubule Plus-end Glycine Biosynthetic Process L-alanine Catabolic Process L-alanine Metabolic Process L-cysteine Catabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis	Structural Constituent Of Chromatin Protein Heterodimerization Activity Nucleosome Chromosome, Telomeric Region Protein-DNA Complex Assembly DNA Binding Nucleosome Assembly Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of Cell Differentiation Sequence-specific DNA Binding Chromatin Remodeling Chromosome Nucleosome Organization Telomere Organization Protein Localization To Chromatin Chromatin Organization Regulation Of Cell Differentiation Nucleus Nucleoplasm Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Developmental Process CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Stem Cell Differentiation Regulation Of Macromolecule Metabolic Process Protein Localization To Chromosome Protein-containing Complex Cardiac Muscle Hypertrophy Positive Regulation Of Proteasomal Protein Catabolic Process Muscle Hypertrophy Regulation Of Cell Development Positive Regulation Of Cartilage Development Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Metabolic Process Acetate CoA-transferase Activity Phenylacetate Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Hepatocyte Homeostasis Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Chromosome Organization Protein Localization To Chromosome, Centromeric Region Regulation Of Megakaryocyte Differentiation Coated Vesicle Membrane
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