MEIOB and FAM107A

Number of citations of the paper that reports this interaction (PubMedID 28604741)
0

Data Source:
BioGRID (two hybrid)

		MEIOB	FAM107A
Description		meiosis specific with OB-fold	family with sequence similarity 107 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm	Stress Fiber Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Nuclear Speck Ruffle Membrane Cell Projection Neuron Projection Synapse Anchoring Junction
	Molecular Function	DNA Binding Chromatin Binding Single-stranded DNA Binding Nuclease Activity Exonuclease Activity Protein Binding Single-stranded DNA 3'-5' DNA Exonuclease Activity Hydrolase Activity	Actin Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates Double-strand Break Repair Via Homologous Recombination Homologous Chromosome Pairing At Meiosis Male Meiotic Nuclear Division Male Meiosis I Female Meiosis I Fertilization Meiotic Cell Cycle	Regulation Of Cell Growth Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: CFTR FAM107A	58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47
Entrez ID		254528	11170
HPRD ID		17530	09753
Ensembl ID		ENSG00000162039	ENSG00000168309
Uniprot IDs		Q8N635	O95990 Q6IAM1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Cellular Response To Lipid Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Negative Regulation Of Long-term Synaptic Potentiation Golgi-associated Vesicle Membrane Cellular Response To Forskolin Chloride Transmembrane Transporter Activity Response To Forskolin Response To Lipid Sperm Capacitation Negative Regulation Of Focal Adhesion Assembly Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Actin Filament Polymerization Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Negative Regulation Of Cell-matrix Adhesion Sterol Biosynthetic Process Regulation Of Long-term Synaptic Potentiation Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cholesterol Transport Cellular Response To CAMP Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Cytoskeleton Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Microtubule Structural Constituent Of Skin Epidermis Meiosis I Cell Cycle Process Female Meiosis I Supramolecular Fiber Organization
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