MSRB3 and PRDM4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MSRB3	PRDM4
Gene Name		methionine sulfoxide reductase B3	PR domain containing 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum	Nucleus
	Molecular Function	Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity	DNA Binding Methyltransferase Activity Zinc Ion Binding
	Biological Process	Response To Oxidative Stress Protein Repair Oxidation-reduction Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Signal Transduction Cell Proliferation Methylation Negative Regulation Of Cell Cycle Neurotrophin TRK Receptor Signaling Pathway
Pathways			Signalling by NGF p75NTR negatively regulates cell cycle via SC1 p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Hippocampal volume ( 22504421) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Temperament ( 22832960) Type 2 diabetes nephropathy ( 21150874)
Protein-Protein Interactions		4 interactors: GOLGA2 PRDM4 TCF4 TRIP6	6 interactors: CTNNBL1 EIF4E EMX1 MSRB3 SERTAD1 SMAD3
Entrez ID		253827	11108
HPRD ID		14785	10425
Ensembl ID		ENSG00000174099	ENSG00000110851
Uniprot IDs		Q8IXL7	B3KPI0 Q9UKN5
PDB IDs			2L9Z 3DB5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Binding Positive Regulation Of Intracellular Protein Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Transport Maintenance Of DNA Repeat Elements Regulation Of Binding Regulation Of Intracellular Protein Transport Release Of Cytoplasmic Sequestered NF-kappaB Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Genitalia Morphogenesis Positive Regulation Of Protein Transport Myoblast Fate Commitment Secretory Granule Localization Hindgut Morphogenesis Insulin Metabolic Process Regulation Of Intracellular Transport Hindgut Development Negative Regulation Of Cell Cycle Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Gluconeogenesis Regulation Of Triglyceride Biosynthetic Process Genitalia Morphogenesis Transcription, DNA-templated Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of NF-kappaB Import Into Nucleus RNA Biosynthetic Process Regulation Of Protein Transport Embryonic Digestive Tract Morphogenesis Regulation Of Establishment Of Protein Localization Regulation Of Glycoprotein Biosynthetic Process Regulation Of Protein Export From Nucleus Cell Proliferation Focal Adhesion Assembly Positive Regulation Of Transport Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Glucose Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Hormone Metabolic Process Face Morphogenesis Regulation Of Protein Localization Negative Regulation Of Organ Growth Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway	Positive Regulation Of Transforming Growth Factor Beta3 Production RNA Processing Evasion Or Tolerance Of Host Defenses By Virus Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Regulation Of Cell Cycle Regulation Of Extracellular Matrix Assembly Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Developmental Growth Cerebral Cortex Regionalization Transdifferentiation Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Alkaline Phosphatase Activity Protein Repair
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