PRDM4 and MSRB3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRDM4	MSRB3
Gene Name		PR domain containing 4	methionine sulfoxide reductase B3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Mitochondrion Endoplasmic Reticulum
	Molecular Function	DNA Binding Methyltransferase Activity Zinc Ion Binding	Zinc Ion Binding Peptide-methionine (R)-S-oxide Reductase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Signal Transduction Cell Proliferation Methylation Negative Regulation Of Cell Cycle Neurotrophin TRK Receptor Signaling Pathway	Response To Oxidative Stress Protein Repair Oxidation-reduction Process
Pathways		Signalling by NGF p75NTR negatively regulates cell cycle via SC1 p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS			Hippocampal volume ( 22504421) Primary tooth development (number of teeth) ( 23704328 20195514) Primary tooth development (time to first tooth eruption) ( 23704328 20195514) Temperament ( 22832960) Type 2 diabetes nephropathy ( 21150874)
Protein-Protein Interactions		6 interactors: CTNNBL1 EIF4E EMX1 MSRB3 SERTAD1 SMAD3	4 interactors: GOLGA2 PRDM4 TCF4 TRIP6
Entrez ID		11108	253827
HPRD ID		10425	14785
Ensembl ID		ENSG00000110851	ENSG00000174099
Uniprot IDs		B3KPI0 Q9UKN5	Q8IXL7
PDB IDs		2L9Z 3DB5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta3 Production RNA Processing Evasion Or Tolerance Of Host Defenses By Virus Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Regulation Of Cell Cycle Regulation Of Extracellular Matrix Assembly Primary MiRNA Processing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway SMAD Protein Complex Assembly Negative Regulation Of Osteoblast Proliferation Developmental Growth Cerebral Cortex Regionalization Transdifferentiation Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Alkaline Phosphatase Activity Protein Repair	Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Binding Positive Regulation Of Intracellular Protein Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Positive Regulation Of Intracellular Transport Maintenance Of DNA Repeat Elements Regulation Of Binding Regulation Of Intracellular Protein Transport Release Of Cytoplasmic Sequestered NF-kappaB Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Genitalia Morphogenesis Positive Regulation Of Protein Transport Myoblast Fate Commitment Secretory Granule Localization Hindgut Morphogenesis Insulin Metabolic Process Regulation Of Intracellular Transport Hindgut Development Negative Regulation Of Cell Cycle Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Gluconeogenesis Regulation Of Triglyceride Biosynthetic Process Genitalia Morphogenesis Transcription, DNA-templated Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of NF-kappaB Import Into Nucleus RNA Biosynthetic Process Regulation Of Protein Transport Embryonic Digestive Tract Morphogenesis Regulation Of Establishment Of Protein Localization Regulation Of Glycoprotein Biosynthetic Process Regulation Of Protein Export From Nucleus Cell Proliferation Focal Adhesion Assembly Positive Regulation Of Transport Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Glucose Metabolic Process Regulation Of Triglyceride Metabolic Process Regulation Of Hormone Metabolic Process Face Morphogenesis Regulation Of Protein Localization Negative Regulation Of Organ Growth Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
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