GAST and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GAST	KIR2DL3
Description		gastrin	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Membrane
	Molecular Function	Hormone Activity Protein Binding	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Food	Immune Response-regulating Signaling Pathway Immune Response
Pathways		G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Oxetacaine
Diseases
GWAS
Interacting Genes		24 interacting genes: AQP6 AQP9 ASPH BCL2L13 CISD2 CP CPE CREB3L1 CYB5R3 ERGIC3 FAM209A GOLM1 GPR152 KIR2DL3 KRT34 LHFPL2 MEP1B MMD MME MUC1 PDZK1IP1 PLP1 SLC10A1 TMEM52B	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		2520	3804
HPRD ID		00671	10383
Ensembl ID		ENSG00000184502	ENSG00000243772
Uniprot IDs		A0A0E3VY36 P01350	E3NZD8 P43628
PDB IDs		5WRJ 7F8V 7F8W 7XOW	1B6U 6PAG 8TUI
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Protein Binding Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cholesterol Binding CD27 Signaling Pathway
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