GAST and CPE

Number of citations of the paper that reports this interaction (PMID 9369230)
1

Data Source:
HPRD (in vivo)

		GAST	CPE
Gene Name		gastrin	carboxypeptidase E
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Nucleus Golgi Apparatus Plasma Membrane Transport Vesicle Membrane Secretory Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Hormone Activity Protein Binding	Carboxypeptidase Activity Metallocarboxypeptidase Activity Zinc Ion Binding Neurexin Family Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Signal Transduction G-protein Coupled Receptor Signaling Pathway	Cardiac Left Ventricle Morphogenesis Cellular Protein Modification Process Proteolysis Neuropeptide Signaling Pathway Metabolic Process Insulin Processing Cellular Protein Metabolic Process Protein Localization To Membrane
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK	Peptide hormone metabolism Insulin processing
Drugs			Insulin Regular Insulin, porcine
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CP CPE MEP1B MME	17 interactors: BDNF CCK CHD3 GAST GCG GTF3C1 INS LRIF1 MED31 NTS PMCH POLA2 POLDIP2 ROBO2 RPA1 TRH UTP14A
Entrez ID		2520	1363
HPRD ID		00671	00272
Ensembl ID		ENSG00000184502	ENSG00000109472
Uniprot IDs		P01350	P16870
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptide Hormone Processing Peptide Metabolic Process Hormone Metabolic Process Cellular Response To UV-A Protein Processing Cellular Amide Metabolic Process Regulation Of Hormone Levels Creatinine Metabolic Process Insulin Processing Response To UV-A Proteolysis Cellular Response To UV-B Insulin Metabolic Process Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Cardiac Left Ventricle Morphogenesis Response To UV-B Replicative Senescence Beta-amyloid Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Copper Ion Transport Toxin Transport Cellular Response To UV Cardiac Ventricle Morphogenesis Cell Aging Cellular Iron Ion Homeostasis	Feeding Behavior Negative Regulation Of Feeding Behavior Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Behavior Regulation Of Feeding Behavior Positive Regulation Of Hormone Secretion Telomere Maintenance Via Semi-conservative Replication G-protein Coupled Receptor Signaling Pathway Nuclear DNA Replication Telomere Maintenance Via Recombination Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Protein Oligomerization Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Eating Behavior DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Glucose Metabolic Process Regulation Of Behavior Behavioral Fear Response Neuron Recognition Positive Regulation Of Protein Secretion Regulation Of Cellular Ketone Metabolic Process Regulation Of Insulin Secretion Fear Response Response To Hormone Regulation Of Peptide Hormone Secretion Regulation Of Gluconeogenesis Cellular Response To Hormone Stimulus Response To Anesthetic Response To Fluoxetine Response To L-glutamate Regulation Of Hormone Secretion Regulation Of Synapse Assembly Positive Regulation Of Insulin Secretion Energy Derivation By Oxidation Of Organic Compounds Positive Regulation Of Protein Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Telomere Maintenance Positive Regulation Of Secretion Negative Regulation Of Glycogen Catabolic Process Negative Regulation Of Negative Chemotaxis Positive Regulation Of Protein Transport Multicellular Organismal Response To Stress Regulation Of Synapse Organization Regulation Of Synapse Structure Or Activity Taste Bud Development Apoptotic Process Involved In Luteolysis Dendrite Extension
Tagcloud ?		17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 krt20 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations	attenuating chimera chimeras cytopathic flanked glycoproteins hamsters hemagglutinin hn illustrated lies llc measles neuraminidase noncytopathic nontranslated noteworthy parainfluenza parent piv1 piv2 piv3 presumed replicates resembles rpiv3 somatitis staged virion
Tagcloud (Difference) ?		17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 krt20 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations	attenuating chimera chimeras cytopathic flanked glycoproteins hamsters hemagglutinin hn illustrated lies llc measles neuraminidase noncytopathic nontranslated noteworthy parainfluenza parent piv1 piv2 piv3 presumed replicates resembles rpiv3 somatitis staged virion
Tagcloud (Intersection) ?