GAST and CP

Number of citations of the paper that reports this interaction (PMID 463490)
0

Data Source:
HPRD (in vitro)

		GAST	CP
Gene Name		gastrin	ceruloplasmin (ferroxidase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Extracellular Region Extracellular Space Lysosomal Membrane Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Hormone Activity Protein Binding	Ferroxidase Activity Copper Ion Binding Chaperone Binding
	Biological Process	Signal Transduction G-protein Coupled Receptor Signaling Pathway	Copper Ion Transport Cellular Iron Ion Homeostasis Transmembrane Transport Oxidation-reduction Process
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK	Metal ion SLC transporters Iron uptake and transport Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport
Drugs			Drotrecogin alfa
Diseases
GWAS			Subcutaneous adipose tissue ( 22589738)
Protein-Protein Interactions		4 interactors: CP CPE MEP1B MME	8 interactors: ATP7A BTRC GAST LTF MPO PLG PROC UBC
Entrez ID		2520	1356
HPRD ID		00671	00317
Ensembl ID		ENSG00000184502	ENSG00000047457
Uniprot IDs		P01350	A5PL27 P00450
PDB IDs			1KCW 2J5W 4EJX 4ENZ
Enriched GO Terms of Interacting Partners?		Peptide Hormone Processing Peptide Metabolic Process Hormone Metabolic Process Cellular Response To UV-A Protein Processing Cellular Amide Metabolic Process Regulation Of Hormone Levels Creatinine Metabolic Process Insulin Processing Response To UV-A Proteolysis Cellular Response To UV-B Insulin Metabolic Process Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Cardiac Left Ventricle Morphogenesis Response To UV-B Replicative Senescence Beta-amyloid Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Copper Ion Transport Toxin Transport Cellular Response To UV Cardiac Ventricle Morphogenesis Cell Aging Cellular Iron Ion Homeostasis	Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Immune System Process Removal Of Superoxide Radicals Cellular Response To Superoxide Response To Superoxide Defense Response To Fungus Response To Oxygen Radical Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteolysis Regulation Of Cell Death Response To Fungus Superoxide Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Response To Stress Negative Regulation Of Wound Healing Response To Stimulus Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Iron Assimilation By Chelation And Transport Hypochlorous Acid Biosynthetic Process Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Elastin Biosynthetic Process Plasma Membrane Copper Ion Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Blood Coagulation Cellular Response To Reactive Oxygen Species Reactive Oxygen Species Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Tissue Remodeling Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Antifungal Humoral Response Positive Regulation Of Bone Mineralization Involved In Bone Maturation Positive Regulation Of Chondrocyte Proliferation Copper Ion Export Negative Regulation Of Osteoclast Development Response To Gold Nanoparticle Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Regulation Of Body Fluid Levels
Tagcloud ?		17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 krt20 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations	airways anesthetized artificially attacks breaths bronchoconstriction citric clarified counteracts endogenously gastroesophageal guinea halved hoe implication inhalation inhaled micromol nerves nk1 nk2 nmma reflux rl sr submaximum tachykinin tachykinins ventilated
Tagcloud (Difference) ?		17q 17q12 amplicon amplification amplifications amplified anthracycline besides ccr7 concerning grb7 heterogeneity heterogeneous igfpb4 iia implications krt19 krt20 locus med1 pitfalls presents rara stard3 subgroup thra top2a topoisomerase variations	airways anesthetized artificially attacks breaths bronchoconstriction citric clarified counteracts endogenously gastroesophageal guinea halved hoe implication inhalation inhaled micromol nerves nk1 nk2 nmma reflux rl sr submaximum tachykinin tachykinins ventilated
Tagcloud (Intersection) ?