KIR2DL3 and TMEM243

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIR2DL3	TMEM243
Description		killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3	transmembrane protein 243
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Membrane
	Molecular Function	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding	Protein Binding
	Biological Process	Immune Response-regulating Signaling Pathway Immune Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Lung cancer in never smokers ( 28604730) Schizophrenia ( 29483656)
Interacting Genes		64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5	46 interacting genes: AQP6 BIK CD33 CD74 CD79A CISD2 CLEC14A CPLX4 CREB3 EBP ELOVL4 ELOVL5 ERGIC3 FAM174A FAM209A FFAR2 GJA8 GPR108 GPR152 GPR37L1 GPX8 HSD17B13 JAGN1 KIR2DL3 LIME1 LMNA LRP10 MRM1 MTIF3 MUC1 PLP1 PSCA RETREG3 RMDN3 SAR1A SCN3B SEC11C SLC10A6 SSMEM1 TMEM101 TMEM14B TMEM35A TMEM45B TMEM80 TMPRSS2 ZFYVE27
Entrez ID		3804	79161
HPRD ID		10383	12911
Ensembl ID		ENSG00000243772	ENSG00000135185
Uniprot IDs		E3NZD8 P43628	C9JY04 Q9BU79
PDB IDs		1B6U 6PAG 8TUI
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cholesterol Binding CD27 Signaling Pathway	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum B Cell Receptor Complex Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Acetylcholine Receptor Regulator Activity Protein Binding Unsaturated Fatty Acid Biosynthetic Process Fatty Acid Elongation, Saturated Fatty Acid Negative Regulation Of Peptide Secretion Fatty Acid Biosynthetic Process Very Long-chain Fatty Acid Biosynthetic Process Endoplasmic Reticulum Organization Fatty Acid Elongation
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