STAC3 and WHSC1L1

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		STAC3	WHSC1L1
Gene Name		SH3 and cysteine rich domain 3	Wolf-Hirschhorn syndrome candidate 1-like 1
Image
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Chromosome
	Molecular Function	Identical Protein Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H3-K4 Specific) Histone Methyltransferase Activity (H3-K27 Specific)
	Biological Process	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development	Chromatin Organization Transcription, DNA-templated Histone Methylation Negative Regulation Of Transcription, DNA-templated Histone H3-K4 Methylation Histone H3-K27 Methylation
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Schizophrenia ( 22037555)
Protein-Protein Interactions		15 interactors: BAZ2B C11orf57 CSNK2A1 DIP2A FAM124A FAM133A FAM90A1 JMJD6 L3MBTL2 MAB21L3 PPARA SREK1IP1 WHSC1L1 ZCCHC10 ZGPAT	17 interactors: CBX3 CBX5 DAXX DOCK7 ETV3 GLYR1 H3F3C HIST1H1A HOXC4 MLLT6 MNDA SEPT6 SLU7 SPAG8 STAC3 UBE2I ZNF557
Entrez ID		246329	54904
HPRD ID		11606	06155
Ensembl ID		ENSG00000185482	ENSG00000147548
Uniprot IDs		B4DUK9 Q96MF2	B7ZL11 Q9BZ95
PDB IDs		2DB6	2DAQ 4GND 4GNE 4GNF 4GNG
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Glycolytic By Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Chromatin Modification Chromatin Organization Negative Regulation Of Receptor Biosynthetic Process Behavioral Response To Nicotine Enamel Mineralization Negative Regulation Of Sequestering Of Triglyceride Negative Regulation Of Cholesterol Storage Regulation Of Cellular Ketone Metabolic Process By Positive Regulation Of Transcription From RNA Polymerase II Promoter Recognition Of Apoptotic Cell Histone H3-K27 Methylation Negative Regulation Of Glycolytic Process Negative Regulation Of Appetite Tooth Mineralization Peptidyl-lysine Modification Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Cellular Metabolic Process Chromosome Organization Rhythmic Process Amelogenesis Negative Regulation Of Transcription Regulatory Region DNA Binding Negative Regulation Of Macrophage Derived Foam Cell Differentiation Cellular Metabolic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of Fatty Acid Oxidation	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cell Division Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Viral Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Establishment Of Neuroblast Polarity Cytokinesis Nucleosome Assembly MRNA 3'-splice Site Recognition Transcription, DNA-templated Chromatin Assembly RNA Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly Gene Expression Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Remodeling DNA Packaging Nucleobase-containing Compound Metabolic Process
Tagcloud ?		abca1 abcg5 abcg8 atorvastatin causal challenging chow excised fads1 gwas hfd hypertensive list loci lpl madd nominally nr1h3 orthologs overlapped pcsk9 pltp qpcr qtl responded spontaneously staged suggestive timd4	aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Difference) ?		abca1 abcg5 abcg8 atorvastatin causal challenging chow excised fads1 gwas hfd hypertensive list loci lpl madd nominally nr1h3 orthologs overlapped pcsk9 pltp qpcr qtl responded spontaneously staged suggestive timd4	aside c5hch cys dimethylase fifth h3k36 h3k4 h3k9 h3k9me0 h3k9me3 homeodomain k9 k9me3 methyltransferases mmset module mono nonredundant nsd nsd1 nsd2 nsd3 phd phd5 shed trimethylated unmethylated unmodified
Tagcloud (Intersection) ?