STAC3 and SPANXN3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		STAC3	SPANXN3
Description		SH3 and cysteine rich domain 3	SPANX family member N3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Voltage-gated Calcium Channel Complex Cytoplasmic Side Of Plasma Membrane Membrane T-tubule Sarcolemma Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Glycated hemoglobin levels ( 34059833) Schizophrenia ( 25056061 29483656)	Creatine kinase levels ( 29403010)
Interacting Genes		38 interacting genes: ANKRD36 BAZ2B C1orf35 CSNK2A1 DIP2A DRC4 EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 FAM9A FGF11 FGF12 GIGYF1 GRB7 HMGXB4 INO80B JMJD6 L3MBTL2 MAB21L3 MFAP1 NKAPD1 NSD3 PPARA RPL22 RPL9 RPS25 SPANXN2 SPANXN3 SREK1IP1 TCEA2 TNFAIP8L1 U2AF2 VCX2 ZCCHC10 ZGPAT	17 interacting genes: APP ATP6V1C2 CAVIN1 CEP70 FAM217B FAM228A HAND2 MEOX2 NEDD4 PBX4 PTGES3L-AARSD1 SDCBP SP4 STAC3 YAF2 ZNF143 ZNF76
Entrez ID		246329	139067
HPRD ID		11606	18092
Ensembl ID		ENSG00000185482	ENSG00000189252
Uniprot IDs		Q96MF2	Q5MJ09
PDB IDs		2DB6 6B29 6UY7 6UY8 6UY9
Enriched GO Terms of Interacting Partners?		Transcription Elongation Factor Complex Super Elongation Complex Transcription Elongation By RNA Polymerase II Transcription Elongation Factor Activity DNA-templated Transcription Elongation Transcription Regulator Activator Activity	Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Toll Signaling Pathway Frizzled Binding Positive Regulation Of DNA-templated Transcription Identical Protein Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Formation Of Structure Involved In A Symbiotic Process Interleukin-5 Receptor Complex Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Semaphorin-plexin Signaling Pathway Positive Regulation Of RNA Metabolic Process Membrane Raft
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