PHF12 and MORF4L1

Number of citations of the paper that reports this interaction (PMID 12391155)
32

Data Source:
HPRD (two hybrid)

		PHF12	MORF4L1
Gene Name		PHD finger protein 12	mortality factor 4 like 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Sin3 Complex Transcriptional Repressor Complex	Nucleoplasm Sin3 Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Transcription Corepressor Binding Protein Binding Zinc Ion Binding Phosphatidylinositol Binding	Chromatin Binding Protein Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated	Double-strand Break Repair Via Homologous Recombination Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Coronary heart disease ( 21378988)
Protein-Protein Interactions		5 interactors: BRCA1 HDAC1 HIST3H3 MORF4L1 SIN3A	35 interactors: APP ARRDC3 BEND7 CALM1 CAMK2B CEP57L1 FAM9B FXR2 GMCL1 GOLGA2 HINFP HIST3H3 HMBOX1 IKZF1 L3MBTL3 LZTS2 MEOX1 MRFAP1 MRFAP1L1 MRGBP MSL1 NAB2 NAV2 PBXIP1 PHF12 RACGAP1 RB1 REL TFCP2 THAP1 TNIP1 TNNT1 TRIM41 ZBTB10 ZBTB9
Entrez ID		57649	10933
HPRD ID		15123	09532
Ensembl ID		ENSG00000109118	ENSG00000185787
Uniprot IDs		Q96QT6	B3KTM8 Q9UBU8
PDB IDs		2L9S 2LKM	2AQL 2EFI 2F5J 2F5K 2LKM
Enriched GO Terms of Interacting Partners?		Histone Deacetylation Protein Deacetylation Negative Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Protein Acetylation Chromosome Organization DNA Metabolic Process Regulation Of Histone Acetylation Histone Modification Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Double-strand Break Repair Via Homologous Recombination Recombinational Repair Negative Regulation Of Chromosome Organization Chromatin Modification Positive Regulation Of Histone H4-K20 Methylation Response To Methylglyoxal Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Histone H3-K27 Acetylation Regulation Of Histone Modification Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Double-strand Break Repair Positive Regulation Of Histone H3-K9 Acetylation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation Of Chromatin Silencing Negative Regulation Of Cell Death Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Cycle Process Negative Regulation Of Transcription, DNA-templated DNA Recombination Cellular Response To Indole-3-methanol Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Negative Regulation Of Centriole Replication DNA Replication Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Cell Cycle Cellular Protein Modification Process	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Gene Expression RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Spindle Midzone Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Transcription, DNA-templated Cell Cycle Immune System Process Multicellular Organismal Development Regulation Of Cell Division Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cell Division Neuron Maturation Cell Maturation Chromatin Modification Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Neutrophil Differentiation Cytokinesis, Initiation Of Separation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade
Tagcloud ?			aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Difference) ?			aligned backgrounds balance chromodomain controlling e3 elegans ensure fate finger germ glp homologue ligases likewise mrg mrg15 notch overproliferation proliferative proper proteasome rfp sensitized spatially stem suppresses threshold tightly
Tagcloud (Intersection) ?