PHF12

Gene Name		PHD finger protein 12
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Sin3 Complex Transcriptional Repressor Complex
	Molecular Function	RNA Polymerase II Transcription Corepressor Activity Transcription Corepressor Binding Protein Binding Zinc Ion Binding Phosphatidylinositol Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: BRCA1 HDAC1 HIST3H3 MORF4L1 SIN3A
Entrez ID		57649
HPRD ID		15123
Ensembl ID		ENSG00000109118
Uniprot IDs		Q96QT6
PDB IDs		2L9S 2LKM
Enriched GO Terms of Interacting Partners?		Histone Deacetylation Protein Deacetylation Negative Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Protein Acetylation Chromosome Organization DNA Metabolic Process Regulation Of Histone Acetylation Histone Modification Organelle Organization Negative Regulation Of Gene Expression, Epigenetic Double-strand Break Repair Via Homologous Recombination Recombinational Repair Negative Regulation Of Chromosome Organization Chromatin Modification Positive Regulation Of Histone H4-K20 Methylation Response To Methylglyoxal Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Histone H3-K27 Acetylation Regulation Of Histone Modification Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Double-strand Break Repair Positive Regulation Of Histone H3-K9 Acetylation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation Of Chromatin Silencing Negative Regulation Of Cell Death Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Cycle Process Negative Regulation Of Transcription, DNA-templated DNA Recombination Cellular Response To Indole-3-methanol Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Negative Regulation Of Centriole Replication DNA Replication Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Cell Cycle Cellular Protein Modification Process
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