TSPAN12 and CDS2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		TSPAN12	CDS2
Name		tetraspanin 12	CDP-diacylglycerol synthase 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Wnt Receptor Activity	Phosphatidate Cytidylyltransferase Activity Protein Binding Transferase Activity Transferase Activity, Transferring Phosphorus-containing Groups Nucleotidyltransferase Activity
	Biological Process	Angiogenesis Cell Surface Receptor Signaling Pathway Retina Layer Formation Maintenance Of Blood-brain Barrier Regulation Of Angiogenesis Norrin Signaling Pathway	Lipid Metabolic Process Phosphatidylglycerol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Biosynthetic Process Lipid Droplet Formation
Pathways		None	Synthesis of PG
Diseases		Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)	None
GWAS		Bitter alcoholic beverage consumption ( 31046077 ) Heel bone mineral density ( 30598549 )	No GWAS studies recorded
Interacting Genes		21 interacting genes: CDS2 CTXN3 CXCL16 CYBC1 EMP3 GPR25 GPR37L1 IGFBP5 MARCHF2 MGST3 NINJ2 PMP22 RFT1 RNF152 STX8 TEX264 TFCP2 TMEM140 TMEM147 TMEM182 TMEM218	28 interacting genes: BIK CPLX4 CREB3 ERGIC3 FAM209A FKBP7 GPR152 GPX8 HIBADH IL10RA JSRP1 LEUTX LHFPL5 LMNA MR1 MTIF3 MYG1 RNF122 SAR1A SSMEM1 TIMMDC1 TMEM139 TMEM45B TMX2 TRIM55 TRIM63 TSG101 TSPAN12
Entrez ID		23554	8760
HPRD ID		15509	09150
Ensembl ID		ENSG00000106025	ENSG00000101290
Uniprot IDs		O95859	O95674
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Membrane Bleb Assembly Endoplasmic Reticulum Membrane Endoplasmic Reticulum	None