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TSPAN12

Name tetraspanin 12
Structure No pdb structure
Interactors 21 interactors: CDS2 CTXN3 CXCL16 CYBC1 EMP3 GPR25 GPR37L1 IGFBP5 MARCHF2 MGST3 NINJ2 PMP22 RFT1 RNF152 STX8 TEX264 TFCP2 TMEM140 TMEM147 TMEM182 TMEM218
GO Annotations Cellular Component
  • Plasma Membrane
  • Membrane
Molecular Function
  • Protein Binding
  • Wnt Receptor Activity
Biological Process
  • Angiogenesis
  • Cell Surface Receptor Signaling Pathway
  • Retina Layer Formation
  • Maintenance Of Blood-brain Barrier
  • Regulation Of Angiogenesis
  • Norrin Signaling Pathway
Diseases
  • Familial exudative vitreoretinopathy (FEVR), including: Exudative vitreoretinopathy 1 (EVR1); Exudative vitreoretinopathy2, X-linked (EVR2); Exudative vitreoretinopathy 4 (EVR4); Exudative vitreoretinopathy 5 (EVR5); Norrie disease (ND)
GWAS
  • Bitter alcoholic beverage consumption ( 31046077 )
  • Heel bone mineral density ( 30598549 )
Entrez ID 23554
HPRD ID 15509
Ensembl ID ENSG00000106025
Uniprot IDs O95859
PDB IDs Not available
GO Terms Enriched among Interactors ?
  • Membrane
  • Bleb Assembly
  • Endoplasmic Reticulum Membrane
  • Endoplasmic Reticulum

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