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RASD2 and GNB2
Number of citations of the paper that reports this interaction (PMID
19255495
)
4
Data Source:
BioGRID
(two hybrid)
RASD2
GNB2
Gene Name
RASD family, member 2
guanine nucleotide binding protein (G protein), beta polypeptide 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Extracellular Space
Lysosomal Membrane
Plasma Membrane
Focal Adhesion
Membrane
Vesicle
Protein Complex
Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
GTPase Activity
GTP Binding
Ubiquitin Conjugating Enzyme Binding
G-protein Beta-subunit Binding
GTPase Activity
Signal Transducer Activity
Calcium Channel Regulator Activity
Protein Binding
Protein Complex Binding
GTPase Binding
Biological Process
Synaptic Transmission, Dopaminergic
Small GTPase Mediated Signal Transduction
Locomotory Behavior
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Sumoylation
Regulation Of CAMP-mediated Signaling
Positive Regulation Of Protein Kinase B Signaling
Energy Reserve Metabolic Process
G-protein Coupled Receptor Signaling Pathway
Synaptic Transmission
Small Molecule Metabolic Process
Cellular Response To Glucagon Stimulus
Pathways
Signaling by GPCR
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 1
Integration of energy metabolism
G alpha (s) signalling events
Activation of GABAB receptors
Glucagon-type ligand receptors
G beta:gamma signalling through PLC beta
Signaling by Wnt
Metabolic disorders of biological oxidation enzymes
G protein gated Potassium channels
Gastrin-CREB signalling pathway via PKC and MAPK
Thromboxane signalling through TP receptor
G alpha (z) signalling events
G alpha (i) signalling events
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
ADP signalling through P2Y purinoceptor 12
Glucagon signaling in metabolic regulation
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Inwardly rectifying K+ channels
G-protein beta:gamma signalling
Opioid Signalling
Activation of Kainate Receptors upon glutamate binding
Aquaporin-mediated transport
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (q) signalling events
GPCR downstream signaling
Platelet homeostasis
Platelet activation, signaling and aggregation
Transmission across Chemical Synapses
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signal amplification
Potassium Channels
G beta:gamma signalling through PI3Kgamma
G alpha (12/13) signalling events
Class B/2 (Secretin family receptors)
Prostacyclin signalling through prostacyclin receptor
GABA B receptor activation
GABA receptor activation
Activation of G protein gated Potassium channels
Vasopressin regulates renal water homeostasis via Aquaporins
Regulation of insulin secretion
GPCR ligand binding
beta-catenin independent WNT signaling
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Ca2+ pathway
G-protein activation
Drugs
Diseases
GWAS
Protein-Protein Interactions
15 interactors:
ACVR1
BMPR1B
GNB1
GNB2
GNB3
PIK3CA
RABAC1
RAF1
SMAD1
SMAD2
SMAD3
SMAD4
SMURF1
SMURF2
TGFBR1
31 interactors:
ANXA7
ATXN10
CAPNS1
CDKN1A
CSNK1A1
FAM118B
FANCA
GADD45A
GNAI1
GNAI2
GNAI3
GNG10
GNG12
GNG13
GNG3
GNG4
GNG5
GNG7
GNGT1
GRB7
GSK3B
ID3
NR3C1
PCBP1
PDHB
RAF1
RASD2
RCC1
STAT5A
TGFBR1
TSC22D1
Entrez ID
23551
2783
HPRD ID
15210
11820
Ensembl ID
ENSG00000100302
ENSG00000172354
Uniprot IDs
Q96D21
P62879
Q6FHM2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Cellular Response To Growth Factor Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Response To Growth Factor
Cell Surface Receptor Signaling Pathway
BMP Signaling Pathway
Response To Organic Substance
SMAD Protein Complex Assembly
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cellular Response To Growth Factor Stimulus
Signal Transduction
Activin Receptor Signaling Pathway
Signaling
Primary MiRNA Processing
Cell Communication
Pattern Specification Process
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Heart Development
Intracellular Signal Transduction
Cardiovascular System Development
Mesoderm Development
Regulation Of Epithelial To Mesenchymal Transition
Cellular Response To Stimulus
Urogenital System Development
Negative Regulation Of Cell Proliferation
Gastrulation
Regulation Of Ossification
Mesenchyme Development
Tissue Development
Mesoderm Formation
Embryonic Pattern Specification
Mesoderm Morphogenesis
Regulation Of Cartilage Development
Positive Regulation Of Signal Transduction
Positive Regulation Of Ossification
Stem Cell Development
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Regulation Of Signal Transduction
Signal Transduction By Phosphorylation
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Response To Stimulus
Cell Fate Commitment
Cellular Response To Glucagon Stimulus
Response To Glucagon
Synaptic Transmission
Energy Reserve Metabolic Process
Energy Derivation By Oxidation Of Organic Compounds
Cellular Response To Peptide Hormone Stimulus
Response To Peptide Hormone
Cellular Response To Peptide
Response To Peptide
Cell-cell Signaling
Response To Hormone
Cellular Response To Hormone Stimulus
Generation Of Precursor Metabolites And Energy
Cell Surface Receptor Signaling Pathway
Response To Organonitrogen Compound
Cellular Response To Organonitrogen Compound
Signal Transduction
Response To Organic Substance
G-protein Coupled Receptor Signaling Pathway
Signaling
Cellular Response To Organic Substance
Cell Communication
Cellular Response To Stimulus
Response To Stimulus
Regulation Of Cellular Process
Regulation Of Adenylate Cyclase Activity
Regulation Of Cyclase Activity
Regulation Of Signal Transduction
Cell Cycle
Regulation Of CAMP Biosynthetic Process
Regulation Of Body Fluid Levels
Regulation Of Signaling
Positive Regulation Of Programmed Cell Death
Regulation Of Phosphorus Metabolic Process
Regulation Of CAMP Metabolic Process
Positive Regulation Of Cell Death
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Metabolic Process
Hemostasis
Positive Regulation Of Signal Transduction
Response To Wounding
Positive Regulation Of Protein Kinase Activity
Activation Of Protein Kinase Activity
Response To Stress
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Positive Regulation Of Kinase Activity
Regulation Of Kinase Activity
Regulation Of Apoptotic Process
Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
abl
alterations
bcr
bez235
braf
canonical
cdkn2a
clustered
coexpression
confer
dimer
disrupt
effectors
encoding
galpha
gbeta
gbetagamma
gnb1
i80
interface
k57
neoplasms
oncogenic
partly
substitution
subunits
targetable
v600k
variants
Tagcloud (Difference)
?
abl
alterations
bcr
bez235
braf
canonical
cdkn2a
clustered
coexpression
confer
dimer
disrupt
effectors
encoding
galpha
gbeta
gbetagamma
gnb1
i80
interface
k57
neoplasms
oncogenic
partly
substitution
subunits
targetable
v600k
variants
Tagcloud (Intersection)
?