RASD2 and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)

		RASD2	RABAC1
Description		RASD family member 2	Rab acceptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity GTP Binding G-protein Beta-subunit Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Synaptic Transmission, Dopaminergic Signal Transduction Locomotory Behavior Positive Regulation Of Protein Sumoylation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Hippocampal volume in mild cognitive impairment ( 29274321) Intelligence (MTAG) ( 29326435) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		16 interacting genes: ACVR1 BMPR1B GNB1 GNB2 GNB3 PIK3CA PIK3R1 RABAC1 RAF1 SMAD1 SMAD2 SMAD3 SMAD4 SMURF1 SMURF2 TGFBR1	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		23551	10567
HPRD ID		15210	05375
Ensembl ID		ENSG00000100302	ENSG00000105404
Uniprot IDs		Q96D21	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		I-SMAD Binding SMAD Binding Enzyme-linked Receptor Protein Signaling Pathway Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Heteromeric SMAD Protein Complex Activin Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Activity, Type I SMAD Protein Signal Transduction Response To Growth Factor Regulation Of Developmental Process R-SMAD Binding BMP Signaling Pathway Intracellular Glucose Homeostasis Cell Surface Receptor Signaling Pathway Regulation Of Cell Differentiation Trophoblast Cell Migration Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway GTPase Binding Pattern Specification Process Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Extracellular Matrix Assembly Gastrulation Osteoblast Differentiation Ameboidal-type Cell Migration Tissue Development Regionalization Transmembrane Receptor Protein Serine/threonine Kinase Activity Co-SMAD Binding Cellular Response To Growth Factor Stimulus Primary MiRNA Processing Embryonic Pattern Specification Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Binding Positive Regulation Of Signal Transduction Regulation Of SMAD Protein Signal Transduction Intracellular Signaling Cassette Response To Transforming Growth Factor Beta Cell Fate Commitment Positive Regulation Of Cell Differentiation Regulation Of Cartilage Development Positive Regulation Of Multicellular Organismal Process Homomeric SMAD Protein Complex Glucose Homeostasis	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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