KAT6B and ATN1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT6B	ATN1
Description		lysine acetyltransferase 6B	atrophin 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleosome Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function	DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Zinc Ion Binding Histone H3 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Histone H3K14 Acetyltransferase Activity Protein-containing Complex Binding Metal Ion Binding Protein-lysine-acetyltransferase Activity	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Chromatin Organization Nucleosome Assembly Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Developmental Process Regulation Of Hemopoiesis	Negative Regulation Of Transcription By RNA Polymerase II Cell Killing Spermatogenesis Central Nervous System Development Determination Of Adult Lifespan Male Gonad Development Post-embryonic Development Cell Migration Maintenance Of Cell Polarity Response To Food Multicellular Organism Growth Positive Regulation Of DNA-templated Transcription Neuron Apoptotic Process
Pathways		HATs acetylate histones	Regulation of PTEN gene transcription
Drugs
Diseases			Dentatorubropallidoluysian atrophy (DRPLA)
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Femur bone mineral density x serum urate levels interaction ( 34046847)	Refractive error ( 32231278)
Interacting Genes		5 interacting genes: ATN1 H3C1 RUNX1 RUNX2 UBE2I	126 interacting genes: AGRN ALG13 ARF3 ATRX BAG3 BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CHRD CPAP CRACR2A CRIP2 CSNK2A1 CTNND2 DGCR6L DMPK DMRT3 DVL1 DVL2 ECM1 EFEMP1 EFEMP2 ETNK2 EWSR1 FBLN1 FBLN2 FBLN5 FXR1 FXR2 GAPDH GCC1 GIGYF1 GRN HGS HINFP HNRNPF HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP12-2 KRTAP15-1 KRTAP19-2 KRTAP19-5 KRTAP4-12 KRTAP6-2 KRTAP9-3 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 OLIG3 P4HA3 PCSK5 PDCD6IP PFKL PIN1 PITX1 PITX2 PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBM14 RBM4B RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SAXO4 SH3RF1 SHANK3 SIAH1 SIAH2 SLC25A48 SLIT1 SPAG5 SS18L1 SSPOP STXBP4 SYVN1 TEKT3 TEP1 TLE1 TLE5 TNFAIP8 TRIP6 TSC1 USP2 USP54 VIM WDR5 WWP1 WWP2 YAP1 ZMYND8 ZNF503 ZSWIM8
Entrez ID		23522	1822
HPRD ID		07065	06311
Ensembl ID		ENSG00000156650	ENSG00000111676
Uniprot IDs		B2RWN8 Q8WYB5	P54259 Q86V38
PDB IDs		5U2J 6OIE 8E4V
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Chondrocyte Differentiation Negative Regulation Of Biosynthetic Process Ligamentous Ossification Stem Cell Proliferation SUMO Conjugating Enzyme Activity Negative Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Ossification Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Osteoblast Fate Commitment Regulation Of RNA Biosynthetic Process Core-binding Factor Complex RING-like Zinc Finger Domain Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Binding Hemopoiesis Regulation Of Metabolic Process Cell Population Proliferation Cardiac Muscle Tissue Regeneration Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation SUMO Ligase Complex Small Protein Activating Enzyme Binding HLH Domain Binding G1 To G0 Transition Involved In Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Protein Domain Specific Binding Nucleus Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation Positive Regulation Of Granulocyte Differentiation Nucleoplasm Regulation Of Odontogenesis Of Dentin-containing Tooth Response To Sodium Phosphate Negative Regulation Of Transcription By RNA Polymerase II Transcription Cis-regulatory Region Binding Negative Regulation Of Granulocyte Differentiation Mitotic Nuclear Membrane Reassembly Peripheral Nervous System Neuron Development Gene Expression Transferase Complex Regulation Of Transcription By RNA Polymerase II Regulation Of Connective Tissue Replacement	Protein Binding Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Developmental Process Extracellular Matrix Structural Constituent Positive Regulation Of Metabolic Process Regulation Of Gene Expression Calcium Ion Binding Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Intermediate Filament Transcription Corepressor Activity Regulation Of Protein Stability Elastic Fiber Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Cell Surface Receptor Signaling Pathway Wnt Signaling Pathway System Development Apoptotic Process DNA-binding Transcription Factor Binding Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Programmed Cell Death Cell Death Histone H3 Acetyltransferase Activity Regulation Of Cell Population Proliferation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Projection Organization Signal Transduction Positive Regulation Of RNA Metabolic Process
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