BICRAL and ARHGDIG

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BICRAL	ARHGDIG
Description		BICRA like chromatin remodeling complex associated protein	Rho GDP dissociation inhibitor gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin SWI/SNF Complex GBAF Complex	Cytoplasm Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	GDP-dissociation Inhibitor Activity Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding GTPase Regulator Activity
	Biological Process	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Stem Cell Population Maintenance	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization
Pathways		Formation of the non-canonical BAF (ncBAF) complex	RHOB GTPase cycle CDC42 GTPase cycle RHOH GTPase cycle RHOG GTPase cycle
Drugs
Diseases
GWAS			Body mass index ( 26426971)
Interacting Genes		25 interacting genes: ARHGDIG ATXN1 BANP BFSP2 CACHD1 CDC5L DTNBP1 DTX2 EXOC8 FNDC3B HGS HSPB2 HSPB2-C11orf52 NFYC NGLY1 NRF1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 SS18L1 TRIM23 USHBP1	12 interacting genes: AGTR1 BICRAL CDC42 CEP170P1 KXD1 MED10 RAC1 RHOA RHOB RHOG RHOH TACC3
Entrez ID		23506	398
HPRD ID		17180	04163
Ensembl ID		ENSG00000112624	ENSG00000242173
Uniprot IDs		Q6AI39	F1T0H7 Q99819
PDB IDs
Enriched GO Terms of Interacting Partners?			Small GTPase-mediated Signal Transduction Actin Filament Organization GTPase Activity GTP Binding Rho Protein Signal Transduction Intracellular Signaling Cassette Supramolecular Fiber Organization Regulation Of Synapse Organization Wnt Signaling Pathway, Planar Cell Polarity Pathway Establishment Or Maintenance Of Cell Polarity Membrane Invagination Non-canonical Wnt Signaling Pathway Positive Regulation Of Stress Fiber Assembly Focal Adhesion Protein Kinase Binding Positive Regulation Of Actin Filament Bundle Assembly G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Postsynapse G Protein Activity Regulation Of Cytoskeleton Organization Thioesterase Binding Endothelial Tube Morphogenesis Regulation Of Stress Fiber Assembly Secretory Granule Membrane Regulation Of Modification Of Postsynaptic Structure Chemotaxis Establishment Of Epithelial Cell Apical/basal Polarity Intracellular Signal Transduction Regulation Of Actin Cytoskeleton Organization Locomotion Angiotensin-activated Signaling Pathway Regulation Of Modification Of Synaptic Structure Actin Cytoskeleton Organization GTP-dependent Protein Binding Establishment Of Apical/basal Cell Polarity Regulation Of Actin Filament-based Process Regulation Of Reactive Oxygen Species Metabolic Process Polarized Epithelial Cell Differentiation Regulation Of Postsynapse Organization Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Positive Regulation Of Developmental Process Actin Filament-based Process Rac Protein Signal Transduction Positive Regulation Of Lamellipodium Assembly Nuclear Migration Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Regulation Of Microtubule Cytoskeleton Organization Establishment Of Epithelial Cell Polarity Cerebral Cortex Cell Migration
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