CAPN7 and UBL7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		CAPN7	UBL7
Description		calpain 7	ubiquitin like 7
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GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Extracellular Exosome	Cytoplasm Cytosol
	Molecular Function	Endopeptidase Activity Cysteine-type Endopeptidase Activity Calcium-dependent Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity MIT Domain Binding	Protein Binding Protein-macromolecule Adaptor Activity Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Proteolysis Positive Regulation Of Epithelial Cell Migration Self Proteolysis	Immune System Process Ubiquitin-dependent Protein Catabolic Process Protein K27-linked Ubiquitination Innate Immune Response Defense Response To Virus Antiviral Innate Immune Response
Pathways		Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Craniofacial microsomia ( 26853712) Eosinophil percentage of white cells ( 32888494) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Metabolite levels ( 23823483)
Interacting Genes		19 interacting genes: ARNT2 AXIN2 CEP63 CTBP2 GOLGA2 IFT88 IST1 MAD1L1 MAGED1 MDM4 PPP1R13B PRPSAP1 TNFAIP1 TRIM27 UBL7 VHL ZBTB9 ZFYVE19 ZNF655	17 interacting genes: AP1G1 BAG6 CAPN7 CD4 CDKN2A ERCC1 ESRRG IDH1 MFHAS1 MYBPH NEDD8 RAD23A RXRB SH3GLB1 UBC VBP1 WWP2
Entrez ID		23473	84993
HPRD ID		05908	16556
Ensembl ID		ENSG00000131375	ENSG00000138629
Uniprot IDs		Q7Z479 Q9Y6W3	Q96S82
PDB IDs		2QFE 8UC6	2CWB 2DEN
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Population Proliferation Identical Protein Binding Cell Division Negative Regulation Of Catabolic Process Regulation Of Cell Cycle Centrosome Negative Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Cytoplasm Ubiquitin-protein Transferase Activity Negative Regulation Of Autophagy Atrioventricular Valve Morphogenesis Negative Regulation Of Cell Cycle Process Midbody Abscission Regulation Of Primary Metabolic Process Mitotic Cytokinetic Process Mitotic Spindle Protein Ubiquitination Flemming Body Spindle Pole Protein Modification By Small Protein Conjugation Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Cytokinetic Process Regulation Of Cell Cycle Process Molecular Adaptor Activity MAD1 Complex Regulation Of Macromolecule Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle Heart Valve Morphogenesis Proteasomal Protein Catabolic Process Post-translational Protein Modification Transcription Repressor Complex Protein Stabilization Mitotic Spindle Assembly Checkpoint MAD1-MAD2 Complex	Replicative Senescence Retinoic Acid Receptor Signaling Pathway Nuclear Steroid Receptor Activity Ubiquitin Protein Ligase Binding Modification-dependent Protein Catabolic Process Protein Tag Activity Proteasome Binding Ubiquitin-specific Protease Binding Macromolecule Catabolic Process Regulation Of Protein Stability Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Proteolysis Polyubiquitin Modification-dependent Protein Binding
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