NCS1 and IL1RAPL1

Number of citations of the paper that reports this interaction (PMID 12783849)
20

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		NCS1	IL1RAPL1
Gene Name		neuronal calcium sensor 1	interleukin 1 receptor accessory protein-like 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Axon Dendrite Dense Core Granule Golgi Cisterna Membrane Intracellular Membrane-bounded Organelle Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cytoplasm Plasma Membrane Cell Surface Integral Component Of Membrane Axon Dendrite Postsynaptic Membrane
	Molecular Function	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding	Receptor Binding Voltage-gated Calcium Channel Activity Protein Binding Interleukin-1 Binding
	Biological Process	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport	Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Regulation Of Neuron Projection Development Neuron Differentiation Negative Regulation Of Exocytosis Positive Regulation Of Dendrite Morphogenesis Calcium Ion Transmembrane Transport Presynaptic Membrane Assembly
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)	Cardiovascular disease risk factors ( 20838585)
Protein-Protein Interactions		9 interactors: ADRBK1 DRD2 DRD3 DRD5 DTX2 IL1RAPL1 KCND2 NBL1 PI4KB	1 interactors: NCS1
Entrez ID		23413	11141
HPRD ID		04500	02193
Ensembl ID		ENSG00000107130
Uniprot IDs		P62166	Q9NZN1
PDB IDs		1G8I 2LCP	1T3G
Enriched GO Terms of Interacting Partners?		Synaptic Transmission, Dopaminergic Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Dopamine Receptor Signaling Pathway Response To Amphetamine Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Receptor Internalization Negative Regulation Of Blood Pressure Response To Cocaine Response To Amine Regulation Of Adenylate Cyclase Activity Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Cyclase Activity Neuron-neuron Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway Receptor Metabolic Process Associative Learning Blood Circulation Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of CAMP Biosynthetic Process Response To Ammonium Ion Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Receptor-mediated Endocytosis Regulation Of CAMP Metabolic Process Positive Regulation Of Renal Sodium Excretion Response To Histamine G-protein Coupled Receptor Internalization Arachidonic Acid Secretion Behavioral Response To Cocaine Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Ion Transmembrane Transport Regulation Of Neurotransmitter Uptake Prepulse Inhibition Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Learning Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Synaptic Transmission, Dopaminergic G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Response To Alkaloid Negative Regulation Of Secretion By Cell Regulation Of Renal Sodium Excretion Negative Regulation Of Adenylate Cyclase Activity Regulation Of Dopamine Secretion Negative Regulation Of Lyase Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Signaling Regulation Of Excretion
Tagcloud ?		17a 17f 1bb augment bet bipolarization car cars cd161 cd28 cd3zeta costimulator exception expand generates hematologic icos il1r nonlymphoid notable note persist persistence redirected redirection rorc th1 th17 transferred	aberrance chip coincided correlations displayed disturbed explain fcrl4 galk2 glycosylation h3k4me3 iga igan methylation microarray microarrays mononuclear nephropathy pbmcs pcr probes ptprn2 qrt quantitative real trimethylation validate validation variations
Tagcloud (Difference) ?		17a 17f 1bb augment bet bipolarization car cars cd161 cd28 cd3zeta costimulator exception expand generates hematologic icos il1r nonlymphoid notable note persist persistence redirected redirection rorc th1 th17 transferred	aberrance chip coincided correlations displayed disturbed explain fcrl4 galk2 glycosylation h3k4me3 iga igan methylation microarray microarrays mononuclear nephropathy pbmcs pcr probes ptprn2 qrt quantitative real trimethylation validate validation variations
Tagcloud (Intersection) ?