NCS1

Gene Name		neuronal calcium sensor 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Axon Dendrite Dense Core Granule Golgi Cisterna Membrane Intracellular Membrane-bounded Organelle Postsynaptic Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding Protein Kinase Binding
	Biological Process	Regulation Of Neuron Projection Development Positive Regulation Of Exocytosis Phosphatidylinositol-mediated Signaling Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)
Protein-protein Interactions		9 interactors: ADRBK1 DRD2 DRD3 DRD5 DTX2 IL1RAPL1 KCND2 NBL1 PI4KB
Entrez ID		23413
HPRD ID		04500
Ensembl ID		ENSG00000107130
Uniprot IDs		P62166
PDB IDs		1G8I 2LCP
Enriched GO Terms of Interacting Partners?		Synaptic Transmission, Dopaminergic Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Dopamine Receptor Signaling Pathway Response To Amphetamine Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Receptor Internalization Negative Regulation Of Blood Pressure Response To Cocaine Response To Amine Regulation Of Adenylate Cyclase Activity Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Cyclase Activity Neuron-neuron Synaptic Transmission Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway Receptor Metabolic Process Associative Learning Blood Circulation Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of CAMP Biosynthetic Process Response To Ammonium Ion Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Receptor-mediated Endocytosis Regulation Of CAMP Metabolic Process Positive Regulation Of Renal Sodium Excretion Response To Histamine G-protein Coupled Receptor Internalization Arachidonic Acid Secretion Behavioral Response To Cocaine Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Ion Transmembrane Transport Regulation Of Neurotransmitter Uptake Prepulse Inhibition Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Learning Regulation Of Circadian Sleep/wake Cycle, Sleep Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Synaptic Transmission, Dopaminergic G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Response To Alkaloid Negative Regulation Of Secretion By Cell Regulation Of Renal Sodium Excretion Negative Regulation Of Adenylate Cyclase Activity Regulation Of Dopamine Secretion Negative Regulation Of Lyase Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Signaling Regulation Of Excretion
Tagcloud ?		17a 17f 1bb augment bet bipolarization car cars cd161 cd28 cd3zeta costimulator exception expand generates hematologic icos il1r nonlymphoid notable note persist persistence redirected redirection rorc th1 th17 transferred