SYNE1

Gene Name		spectrin repeat containing, nuclear envelope 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Outer Membrane Nucleoplasm Cytoplasm Golgi Apparatus Cytoskeleton Integral Component Of Membrane Sarcomere Nuclear Membrane LINC Complex Postsynaptic Membrane
	Molecular Function	Actin Binding Protein Binding Lamin Binding Protein Homodimerization Activity Poly(A) RNA Binding Actin Filament Binding
	Biological Process	Nucleus Organization Golgi Organization Establishment Of Nucleus Localization Muscle Cell Differentiation Cytoskeletal Anchoring At Nuclear Membrane Nuclear Matrix Anchoring At Nuclear Membrane
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 21926972 21738484) Bipolar disorder and major depressive disorder (combined) ( 20351715) Tonometry ( 17903302)
Protein-protein Interactions		15 interactors: ACTC1 APC CAPN1 CDC42 CDC5L CEP63 DISC1 DTNBP1 EMD KIAA0368 LMNA MUSK NDEL1 SH3BP5 TNIK
Entrez ID		23345
HPRD ID		09762
Ensembl ID		ENSG00000131018
Uniprot IDs		Q8NF91
PDB IDs		4DXR
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Endomembrane System Organization Microtubule-based Process Nuclear Envelope Disassembly Organelle Organization Microtubule Cytoskeleton Organization Cell Differentiation Membrane Organization Nuclear Envelope Organization Regulation Of Cell Projection Organization Mitotic Nuclear Envelope Reassembly Wnt Signaling Pathway Cell Cycle Process Regulation Of Synapse Organization Nuclear Envelope Reassembly Regulation Of Synapse Structure Or Activity Canonical Wnt Signaling Pathway Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Phosphorylation Striated Muscle Tissue Development Mitotic Cell Cycle Process Muscle Tissue Development Nucleus Organization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Mitotic Cell Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Cellular Component Organization Regulation Of Phosphorylation Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Cell Cycle Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Modification Process Movement Of Cell Or Subcellular Component Regulation Of Protein Metabolic Process Establishment Or Maintenance Of Cell Polarity Regulation Of Signaling Cardiac Muscle Tissue Development Generation Of Neurons Muscle Structure Development Mitotic Nuclear Envelope Disassembly System Development Regulation Of Cellular Localization Neurogenesis Cellular Localization
Tagcloud ?		aimed cdna controls correlation distributed encompasses esr1 follicular genotyped genotyping investigating menstrual menstrually migraine mm mrm pgr plink pmm potentially pure qpcr rs3093664 rs9371601 rstudio snps tnf undertaking variants