SYNE1 and KIAA0368

Number of citations of the paper that reports this interaction (PMID 20682791)
15

Data Source:
BioGRID (two hybrid)

		SYNE1	KIAA0368
Gene Name		spectrin repeat containing, nuclear envelope 1	KIAA0368
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Outer Membrane Nucleoplasm Cytoplasm Golgi Apparatus Cytoskeleton Integral Component Of Membrane Sarcomere Nuclear Membrane LINC Complex Postsynaptic Membrane	Proteasome Complex Nucleus Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane Cytoplasmic Membrane-bounded Vesicle ER To Golgi Transport Vesicle Endocytic Vesicle
	Molecular Function	Actin Binding Protein Binding Lamin Binding Protein Homodimerization Activity Poly(A) RNA Binding Actin Filament Binding	Molecular_function
	Biological Process	Nucleus Organization Golgi Organization Establishment Of Nucleus Localization Muscle Cell Differentiation Cytoskeletal Anchoring At Nuclear Membrane Nuclear Matrix Anchoring At Nuclear Membrane	ER-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Meiotic synapsis
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 21926972 21738484) Bipolar disorder and major depressive disorder (combined) ( 20351715) Tonometry ( 17903302)
Protein-Protein Interactions		15 interactors: ACTC1 APC CAPN1 CDC42 CDC5L CEP63 DISC1 DTNBP1 EMD KIAA0368 LMNA MUSK NDEL1 SH3BP5 TNIK	28 interactors: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREML GOLGB1 HNRNPM MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		23345	23392
HPRD ID		09762	11078
Ensembl ID		ENSG00000131018	ENSG00000136813
Uniprot IDs		Q8NF91	J3KN16 Q5VYK3
PDB IDs		4DXR
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Endomembrane System Organization Microtubule-based Process Nuclear Envelope Disassembly Organelle Organization Microtubule Cytoskeleton Organization Cell Differentiation Membrane Organization Nuclear Envelope Organization Regulation Of Cell Projection Organization Mitotic Nuclear Envelope Reassembly Wnt Signaling Pathway Cell Cycle Process Regulation Of Synapse Organization Nuclear Envelope Reassembly Regulation Of Synapse Structure Or Activity Canonical Wnt Signaling Pathway Positive Regulation Of Pseudopodium Assembly Regulation Of Protein Phosphorylation Striated Muscle Tissue Development Mitotic Cell Cycle Process Muscle Tissue Development Nucleus Organization Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Mitotic Cell Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Cellular Component Organization Regulation Of Phosphorylation Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Signal Transduction Cell Cycle Multicellular Organismal Development Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Modification Process Movement Of Cell Or Subcellular Component Regulation Of Protein Metabolic Process Establishment Or Maintenance Of Cell Polarity Regulation Of Signaling Cardiac Muscle Tissue Development Generation Of Neurons Muscle Structure Development Mitotic Nuclear Envelope Disassembly System Development Regulation Of Cellular Localization Neurogenesis Cellular Localization	ER-associated Ubiquitin-dependent Protein Catabolic Process Nucleus Localization Cell Cycle Establishment Of Nucleus Localization Cell Cycle Process Positive Regulation Of DNA Repair Cell Division Endomembrane System Organization Negative Regulation Of Muscle Cell Differentiation Histone H2A-K13 Ubiquitination Protein Localization To T-tubule Histone H2A-K15 Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of DNA Repair Histone H2A K63-linked Ubiquitination T-tubule Organization Protein Localization To M-band Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Response To DNA Damage Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process
Tagcloud ?		aimed cdna controls correlation distributed encompasses esr1 follicular genotyped genotyping investigating menstrual menstrually migraine mm mrm pgr plink pmm potentially pure qpcr rs3093664 rs9371601 rstudio snps tnf undertaking variants
Tagcloud (Difference) ?		aimed cdna controls correlation distributed encompasses esr1 follicular genotyped genotyping investigating menstrual menstrually migraine mm mrm pgr plink pmm potentially pure qpcr rs3093664 rs9371601 rstudio snps tnf undertaking variants
Tagcloud (Intersection) ?