ICE1 and AIMP2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ICE1	AIMP2
Gene Name		interactor of little elongation complex ELL subunit 1	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Elongation Factor Complex Cajal Body Transcriptionally Active Chromatin Histone Locus Body	Nucleus Cytosol Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Positive Regulation Of Protein Complex Assembly SnRNA Transcription From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Intracellular Protein Transport	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation
Pathways			Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: AIMP2 BTRC	48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		23379	7965
HPRD ID		11119	02915
Ensembl ID		ENSG00000164151	ENSG00000106305
Uniprot IDs		Q9Y2F5	A8MU58 Q13155
PDB IDs			4DPG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation Tube Development Lung Secretory Cell Differentiation Positive Regulation Of Protein Modification Process Positive Regulation Of Circadian Rhythm Mammary Gland Epithelial Cell Proliferation SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Epithelium Development Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Smoothened Signaling Pathway Positive Regulation Of Protein Metabolic Process Branching Involved In Mammary Gland Duct Morphogenesis Lung Epithelial Cell Differentiation Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Lung Cell Differentiation Mammary Gland Duct Morphogenesis Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Tissue Development Lung Epithelium Development Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Cellular Protein Metabolic Process Mammary Gland Morphogenesis Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Epithelial Cell Proliferation Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Circadian Rhythm Regulation Of Smoothened Signaling Pathway Mammary Gland Epithelium Development Regulation Of Protein Metabolic Process TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Stability	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process
Tagcloud ?			4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Difference) ?			4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Intersection) ?