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RPA1 and POLL
Number of citations of the paper that reports this interaction (PubMedID
17507928
)
0
Data Source:
HPRD
(in vitro)
RPA1
POLL
Description
replication protein A1
DNA polymerase lambda
Image
GO Annotations
Cellular Component
Nuclear Chromosome
Chromosome, Telomeric Region
Condensed Chromosome
Condensed Nuclear Chromosome
Lateral Element
Male Germ Cell Nucleus
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
PML Body
Site Of Double-strand Break
Site Of DNA Damage
Nucleus
Nucleoplasm
Chromosome
Site Of Double-strand Break
Molecular Function
Nucleic Acid Binding
DNA Binding
Chromatin Binding
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Zinc Ion Binding
Single-stranded Telomeric DNA Binding
Metal Ion Binding
G-rich Strand Telomeric DNA Binding
Chromatin-protein Adaptor Activity
DNA Binding
DNA-directed DNA Polymerase Activity
Protein Binding
Transferase Activity
Nucleotidyltransferase Activity
Lyase Activity
DNA Polymerase Activity
Metal Ion Binding
5'-deoxyribose-5-phosphate Lyase Activity
Biological Process
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
In Utero Embryonic Development
DNA Replication
DNA-templated DNA Replication
DNA Repair
Base-excision Repair
Nucleotide-excision Repair
Mismatch Repair
DNA Recombination
Chromatin Organization
DNA Damage Response
Telomere Maintenance Via Telomerase
Positive Regulation Of Cell Population Proliferation
Hemopoiesis
Protein Localization To Chromosome
Homeostasis Of Number Of Cells Within A Tissue
Chromosome Organization
Meiotic Cell Cycle
Protein Localization To Site Of Double-strand Break
Double-strand Break Repair Via Homologous Recombination
DNA Replication
DNA Repair
Base-excision Repair, Gap-filling
Nucleotide-excision Repair
Double-strand Break Repair Via Nonhomologous End Joining
DNA Damage Response
Somatic Hypermutation Of Immunoglobulin Genes
DNA Biosynthetic Process
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Removal of the Flap Intermediate from the C-strand
Activation of ATR in response to replication stress
SUMOylation of DNA damage response and repair proteins
Regulation of HSF1-mediated heat shock response
HSF1 activation
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Formation of Incision Complex in GG-NER
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Fanconi Anemia Pathway
Regulation of TP53 Activity through Phosphorylation
Activation of the pre-replicative complex
Removal of the Flap Intermediate
G2/M DNA damage checkpoint
Meiotic recombination
Impaired BRCA2 binding to RAD51
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Airway imaging phenotypes (
26030696
)
Bipolar disorder (
31043756
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
27863252
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Metabolite levels (
23823483
)
Interacting Genes
70 interacting genes:
AICDA
AJUBA
AKTIP
ASCC2
ATM
ATR
BLM
BRCA2
BRIP1
CCNA1
CEBPA
CPE
CSNK2B
DMC1
EHMT2
ERCC1
ERCC4
GNB5
GRB2
HAX1
HELB
HGH1
HIRA
HNRNPUL1
HSPA6
HUS1
KAT2A
KAT2B
MCM2
MCM7
MMS22L
MSH4
MTUS2
MUTYH
ORC2
ORC6
PAXIP1
PCNA
POLL
PRIMPOL
PRKDC
PRPF19
RAD1
RAD23B
RAD51
RAD52
RAD9A
RBM23
RECQL
RFWD3
RIPK1
RNF20
RNF40
RPA2
RPA3
RPA4
RPS6KA5
SELENBP1
SEM1
SMAD3
TCEA2
TK1
TP53
TREX1
VIM
WAS
WRN
XPA
XPC
ZBTB14
42 interacting genes:
APP
ATM
CCNDBP1
CDK1
CDK2
CMTM5
FAM9B
FSD2
GOLGA6L9
HMBOX1
HUWE1
KRT16
KRT19
KRT27
KRT40
KRTAP10-3
KRTAP10-7
LCN2
LDOC1
MAGEA12
MAGEA2
MAGEA2B
MAL2
MCC
MDFI
PCNA
PICK1
PNMA1
PRKD3
REV1
RPA1
SSX2IP
TFCP2
TFIP11
TNFRSF10D
TRIM23
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2H
ZRANB1
Entrez ID
6117
27343
HPRD ID
01565
09394
Ensembl ID
ENSG00000132383
ENSG00000166169
Uniprot IDs
P27694
A8K860
B4DE17
Q5JQP8
Q9UGP5
PDB IDs
1EWI
1FGU
1JMC
1L1O
2B29
2B3G
4IJH
4IJL
4IPC
4IPD
4IPG
4IPH
4LUO
4LUV
4LUZ
4LW1
4LWC
4NB3
4O0A
4R4C
4R4I
4R4O
4R4Q
4R4T
5E7N
5EAY
5N85
5N8A
7XUT
7XUV
7XUW
7XV0
7XV1
7XV4
8JZV
8JZY
8K00
8RK2
9J1S
9MJ5
1NZP
1RZT
1XSL
1XSN
1XSP
2BCQ
2BCR
2BCS
2BCU
2BCV
2GWS
2JW5
2PFN
2PFO
2PFP
2PFQ
3C5F
3C5G
3HW8
3HWT
3HX0
3MDA
3MDC
3MGH
3MGI
3PML
3PMN
3PNC
3UPQ
3UQ0
3UQ2
4FO6
4K4G
4K4H
4K4I
4X5V
4XA5
4XQ8
4XRH
4XUS
5CA7
5CB1
5CHG
5CJ7
5CP2
5CR0
5CWR
5DDM
5DDY
5DKW
5III
5IIJ
5IIK
5IIL
5IIM
5IIN
5IIO
5W4G
7M07
7M08
7M09
7M0A
7M0B
7M0C
7M0D
7M0E
7M43
7M44
7M45
7M46
7M47
7M48
7M49
7M4A
7M4B
7M4C
7M4D
7M4E
7M4F
7M4G
7M4H
7M4I
7M4J
7M4K
7M4L
7UN7
8U0O
Enriched GO Terms of Interacting Partners
?
DNA Metabolic Process
DNA Repair
DNA Damage Response
DNA Recombination
Cellular Response To Stress
Double-strand Break Repair
Nucleic Acid Metabolic Process
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Nucleus
Nucleobase-containing Compound Metabolic Process
Response To Stress
Signal Transduction In Response To DNA Damage
Macromolecule Metabolic Process
Single-stranded DNA Binding
Cellular Response To Radiation
Nucleoplasm
DNA Replication
Nucleotide-excision Repair
DNA Damage Checkpoint Signaling
Response To Ionizing Radiation
Response To Radiation
Site Of Double-strand Break
Replication Fork Processing
Chromosome, Telomeric Region
Chromosome Organization
Cellular Response To Ionizing Radiation
Telomere Maintenance
Regulation Of DNA Metabolic Process
Negative Regulation Of Cell Cycle Process
Negative Regulation Of Cell Cycle
Telomere Organization
Negative Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle Phase Transition
Mitotic DNA Damage Checkpoint Signaling
Chromosome
Regulation Of Cell Cycle
Mismatch Repair
Mitotic DNA Integrity Checkpoint Signaling
Regulation Of Cell Cycle Process
Response To UV
Regulation Of Cellular Response To Stress
DNA Binding
Regulation Of Nucleobase-containing Compound Metabolic Process
Damaged DNA Binding
DNA Replication Factor A Complex
MutLalpha Complex Binding
Response To Gamma Radiation
Mitotic Recombination
DNA Helicase Activity
Ubiquitin Conjugating Enzyme Activity
Telomere Maintenance
Chromosome, Telomeric Region
Keratin Filament
Protein K48-linked Ubiquitination
Telomere Organization
Ubiquitin-protein Transferase Activity
DNA Biosynthetic Process
Intermediate Filament
Post-translational Protein Modification
Protein Polyubiquitination
Nucleus
DNA Metabolic Process
Protein Monoubiquitination
Structural Constituent Of Skin Epidermis
Cellular Senescence
Cyclin-dependent Protein Kinase Activity
Chromosome Organization
DNA Repair
DNA Replication
Intermediate Filament Organization
Protein Localization To Site Of Double-strand Break
Negative Regulation Of Protein Acetylation
Negative Regulation Of Transcription By RNA Polymerase II
Protein Modification Process
Histone Kinase Activity
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
DNA Damage Response
Protein Ubiquitination
Protection From Non-homologous End Joining At Telomere
Cellular Response To Reactive Oxygen Species
Positive Regulation Of DNA Replication
Positive Regulation Of Protein Ubiquitination
PML Body
Cyclin-dependent Protein Kinase Holoenzyme Complex
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Protein Modification By Small Protein Conjugation
Cellular Response To X-ray
Negative Regulation Of Protein Sumoylation
Male Germ Cell Nucleus
Positive Regulation Of Post-translational Protein Modification
Ubiquitin-dependent Protein Catabolic Process
Nucleoplasm
Epithelial Cell Differentiation
Modification-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Protein Binding
DNA Strand Resection Involved In Replication Fork Processing
Telomere Maintenance In Response To DNA Damage
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Tagcloud (Intersection)
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