NCDN and SEMA4C

Number of citations of the paper that reports this interaction (PubMedID 11162505)
0

Data Source:
HPRD (in vivo, in vitro)

		NCDN	SEMA4C
Description		neurochondrin	semaphorin 4C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cytosol Endosome Membrane Membrane Axon Dendrite Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Synapse Postsynapse Glutamatergic Synapse	Extracellular Space Plasma Membrane Postsynaptic Density Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Neuron Projection Development Bone Resorption Regulation Of Neuronal Synaptic Plasticity Regulation Of Postsynaptic Neurotransmitter Receptor Internalization	Neural Crest Cell Migration Neural Tube Closure Nervous System Development Axon Guidance Cell Migration In Hindbrain Cerebellum Development Cell Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Stress-activated MAPK Cascade Muscle Cell Differentiation Negative Chemotaxis Semaphorin-plexin Signaling Pathway Regulation Of Postsynapse Assembly
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		13 interacting genes: A2M ACD EFHC2 KRT75 LYST PAX6 POT1 PREX1 SEMA4C TINF2 TLE5 ZBED1 ZNF398	20 interacting genes: CYSRT1 DLG1 DLG2 DLG3 DLG4 GIPC1 HSF2BP KRT16 KRT27 KRT31 KRT34 KRT40 KRTAP6-3 NBPF19 NCDN NOTCH2NLA PNMA1 RCHY1 TRIM54 USHBP1
Entrez ID		23154	54910
HPRD ID		10530	07257
Ensembl ID		ENSG00000020129	ENSG00000168758
Uniprot IDs		Q9UBB6	Q9C0C4
PDB IDs			6N5Z
Enriched GO Terms of Interacting Partners?		Telomere Assembly Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Regulation Of DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Cell Motility Telomere Maintenance Via Telomerase Telomere Organization Negative Regulation Of DNA Metabolic Process RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Chromosome, Telomeric Region Cell Migration Leukocyte Migration Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein Autosumoylation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Regulation Of Chromosome Organization Positive Regulation Of DNA Metabolic Process Negative Regulation Of Complement Activation, Lectin Pathway Mast Cell Secretory Granule Organization Positive Regulation Of Telomeric Loop Disassembly Perinucleolar Chromocenter Interleukin-8 Binding Chemotaxis Habenula Development Pallium Development DNA Biosynthetic Process 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Chromosome Organization Locomotion	Structural Constituent Of Skin Epidermis Intermediate Filament Intermediate Filament Organization Ionotropic Glutamate Receptor Binding Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Receptor Localization To Synapse Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Protein Localization To Synapse Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Morphogenesis Of An Epithelium Structural Molecule Activity Neuromuscular Junction Protein Localization To Cell Junction Tissue Morphogenesis Kinase Binding Postsynaptic Density Membrane Supramolecular Fiber Organization Epidermis Development Chemical Synaptic Transmission Establishment Or Maintenance Of Cell Polarity Neuron Projection Trans-synaptic Signaling Synaptic Signaling GMP Kinase Activity Adherens Junction GDP Metabolic Process Epithelial Cell Differentiation Juxtaparanode Region Of Axon Cellular Response To Potassium Ion Anatomical Structure Morphogenesis Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Response To Potassium Ion Glutamatergic Synapse Protein Localization To Membrane Cytosol AMPA Glutamate Receptor Complex GMP Metabolic Process Cell-cell Signaling Protein Localization To Postsynaptic Membrane Signaling Protein Localization To Postsynapse Cytoskeleton Organization Cell Communication Establishment Of Skin Barrier Skin Epidermis Development Developmental Process
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