NCDN and LYST

Number of citations of the paper that reports this interaction (PubMedID 11984006)
0

Data Source:
HPRD (two hybrid, in vivo)

		NCDN	LYST
Description		neurochondrin	lysosomal trafficking regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Cytosol Endosome Membrane Membrane Axon Dendrite Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Synapse Postsynapse Glutamatergic Synapse	Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Neuron Projection Development Bone Resorption Regulation Of Neuronal Synaptic Plasticity Regulation Of Postsynaptic Neurotransmitter Receptor Internalization	Lymphocyte Mediated Immunity Phagocytosis Immune Response Protein Transport Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Defense Response To Other Organism
Pathways
Drugs
Diseases			Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS			Basophil percentage of white cells ( 32888494) Lymphocyte count ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 19838195 26502338)
Interacting Genes		13 interacting genes: A2M ACD EFHC2 KRT75 LYST PAX6 POT1 PREX1 SEMA4C TINF2 TLE5 ZBED1 ZNF398	23 interacting genes: ATN1 CALM1 CELF4 CNTROB CPAP CSNK2B DNAJC14 EFS ESRRA ESS2 HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ ZNF521
Entrez ID		23154	1130
HPRD ID		10530	06060
Ensembl ID		ENSG00000020129	ENSG00000143669
Uniprot IDs		Q9UBB6	Q99698
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Assembly Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Regulation Of DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Cell Motility Telomere Maintenance Via Telomerase Telomere Organization Negative Regulation Of DNA Metabolic Process RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Chromosome, Telomeric Region Cell Migration Leukocyte Migration Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Protein Autosumoylation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Regulation Of Chromosome Organization Positive Regulation Of DNA Metabolic Process Negative Regulation Of Complement Activation, Lectin Pathway Mast Cell Secretory Granule Organization Positive Regulation Of Telomeric Loop Disassembly Perinucleolar Chromocenter Interleukin-8 Binding Chemotaxis Habenula Development Pallium Development DNA Biosynthetic Process 8-hydroxy-2'-deoxyguanosine DNA Binding Telomeric G-quadruplex DNA Binding Chromosome Organization Locomotion	Protein Domain Specific Binding Regulation Of Receptor Signaling Pathway Via JAK-STAT Calcium Channel Inhibitor Activity Astral Microtubule Organization Ribonucleoprotein Complex Alternative MRNA Splicing, Via Spliceosome Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Centriole Replication Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Multivesicular Body Organization Multivesicular Body Assembly Centriole Assembly
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