FCHO1 and ZBTB24

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FCHO1	ZBTB24
Description		FCH and mu domain containing endocytic adaptor 1	zinc finger and BTB domain containing 24
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin-coated Vesicle Postsynaptic Endocytic Zone	Nucleus
	Molecular Function	Protein Binding AP-2 Adaptor Complex Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Endocytosis Clathrin Coat Assembly T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Clathrin-dependent Endocytosis	Hematopoietic Progenitor Cell Differentiation Regulation Of Transcription By RNA Polymerase II
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)	Depression in smokers ( 30219690) Height ( 18391951 20881960)
Interacting Genes		51 interacting genes: ACVR1 APP BYSL CCDC13 CFTR CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15L1 EXOSC5 FBXL7 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688	70 interacting genes: BACH2 BAX BCL11A BLZF1 CALM1 CCDC136 CCNDBP1 CDA CEP70 CEP76 DDHD1 DNM1L DVL3 FCHO1 GMCL1 GOLGA6L9 HMBOX1 KDM1A KLF15 KPNA3 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP4-2 KRTAP5-9 LDOC1 LHX8 LNX1 LRRC18 MCIDAS MDFI MID2 NFE2L2 PDE4DIP PHC2 PICK1 POGZ POU6F2 PRMT7 RALY RBM10 RIN3 SPMIP2 SSX2IP SUV39H1 TLE5 TMEM121 TRAF2 TRIM37 TRIM41 TSC22D4 TSGA10 TSPYL2 ZBTB43 ZBTB8A ZBTB9 ZMYM6 ZNF526 ZNF639 ZNF79 ZNF792 ZNF837 ZRANB1
Entrez ID		23149	9841
HPRD ID		16887	18315
Ensembl ID		ENSG00000130475	ENSG00000112365
Uniprot IDs		A0A0C3SFZ9 A0A8V8TMX9 A0A8V8TNC3 A0A8V8TPM7 B7ZAZ3 M0QYA9 O14526	O43167
PDB IDs		7OHI
Enriched GO Terms of Interacting Partners?		Intermediate Filament Clathrin-coated Pit Protein Targeting To Vacuole Involved In Autophagy Endosome To Plasma Membrane Transport Vesicle Regulation Of SMAD Protein Signal Transduction Low-density Lipoprotein Particle Receptor Binding Cytosol Positive Regulation Of Aggrephagy Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Enamel Mineralization Clathrin Coat Of Coated Pit Keratin Filament Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Vesicle-mediated Transport Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Binding Regulation Of Growth Receptor Metabolic Process SMAD Binding Negative Regulation Of Protein Localization Protein Targeting To Vacuole Negative Regulation Of Growth	Keratin Filament Intermediate Filament Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Zinc Ion Binding Protein Binding Regulation Of RNA Metabolic Process
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