FCHO1 and MAB21L3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FCHO1	MAB21L3
Description		FCH and mu domain containing endocytic adaptor 1	mab-21 like 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin-coated Vesicle Postsynaptic Endocytic Zone
	Molecular Function	Protein Binding AP-2 Adaptor Complex Binding	Protein Binding
	Biological Process	Endocytosis Clathrin Coat Assembly T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Clathrin-dependent Endocytosis
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Basophil count ( 32888494) Coronary artery disease ( 29212778) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Monocyte percentage of white cells ( 32888494) Myocardial infarction ( 33532862)	Coffee consumption ( 29367735) HDL cholesterol levels in HIV infection ( 33109212) Macular thickness ( 30535121)
Interacting Genes		51 interacting genes: ACVR1 APP BYSL CCDC13 CFTR CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15L1 EXOSC5 FBXL7 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688	28 interacting genes: ABT1 AGGF1 ANKRD36B AP2M1 BEGAIN CT45A1 DVL3 EAF1 EHHADH EMD FAM9B FCHO1 GPATCH2L INO80E KRTAP10-9 KXD1 LBX1 LENG1 LZTS2 MED4 NTAQ1 PHC2 SPG21 SPRED1 STAC3 WHR1 ZCCHC10 ZNF165
Entrez ID		23149	126868
HPRD ID		16887	08245
Ensembl ID		ENSG00000130475	ENSG00000173212
Uniprot IDs		A0A0C3SFZ9 A0A8V8TMX9 A0A8V8TNC3 A0A8V8TPM7 B7ZAZ3 M0QYA9 O14526	Q8N8X9
PDB IDs		7OHI
Enriched GO Terms of Interacting Partners?		Intermediate Filament Clathrin-coated Pit Protein Targeting To Vacuole Involved In Autophagy Endosome To Plasma Membrane Transport Vesicle Regulation Of SMAD Protein Signal Transduction Low-density Lipoprotein Particle Receptor Binding Cytosol Positive Regulation Of Aggrephagy Negative Regulation Of Protein Localization To Plasma Membrane Regulation Of Enamel Mineralization Clathrin Coat Of Coated Pit Keratin Filament Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Regulation Of Vesicle-mediated Transport Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Binding Regulation Of Growth Receptor Metabolic Process SMAD Binding Negative Regulation Of Protein Localization Protein Targeting To Vacuole Negative Regulation Of Growth
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