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CDK19 and BCL6
Number of citations of the paper that reports this interaction (PMID
22668559
)
1
Data Source:
BioGRID
(pull down, pull down)
CDK19
BCL6
Gene Name
cyclin-dependent kinase 19
B-cell CLL/lymphoma 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Replication Fork
Molecular Function
Cyclin-dependent Protein Serine/threonine Kinase Activity
ATP Binding
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Chromatin DNA Binding
Sequence-specific DNA Binding
Metal Ion Binding
Biological Process
Protein Phosphorylation
Regulation Of Cell Cycle
Protein Import Into Nucleus, Translocation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Morphogenesis
Negative Regulation Of Cell-matrix Adhesion
Germinal Center Formation
Regulation Of Germinal Center Formation
Negative Regulation Of B Cell Apoptotic Process
Transcription, DNA-templated
Inflammatory Response
Cellular Response To DNA Damage Stimulus
Rho Protein Signal Transduction
Spermatogenesis
Negative Regulation Of Cell Proliferation
Actin Cytoskeleton Organization
B Cell Differentiation
Negative Regulation Of Cell Growth
Positive Regulation Of B Cell Proliferation
Positive Regulation Of Histone Deacetylation
Regulation Of Rho GTPase Activity
Negative Regulation Of Mast Cell Cytokine Production
Negative Regulation Of Rho Protein Signal Transduction
Type 2 Immune Response
Positive Regulation Of Apoptotic Process
Regulation Of Memory T Cell Differentiation
Negative Regulation Of T-helper 2 Cell Differentiation
Positive Regulation Of Neuron Differentiation
Negative Regulation Of Notch Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Isotype Switching To IgE Isotypes
Erythrocyte Development
Regulation Of Inflammatory Response
Regulation Of Immune Response
Positive Regulation Of Cellular Component Movement
Negative Regulation Of Cellular Senescence
Pathways
PPARA activates gene expression
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Transcriptional regulation of white adipocyte differentiation
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
B cell non-Hodgkin lymphoma (
23749188
)
PR interval (
23534349
)
Pulmonary function (interaction) (
23284291
)
Renal function-related traits (BUN) (
22797727
)
Protein-Protein Interactions
5 interactors:
BCL6
EIF3F
SMARCA4
SRSF7
SUZ12
44 interactors:
AES
BCL11A
BCL6B
BCOR
BLZF1
CDK19
CDK8
CHD3
CREBBP
CUTC
EP300
FBXO11
HDAC4
HDAC5
HDAC7
HDAC9
IRF4
JUN
JUNB
JUND
KIFC3
LIMS3
MAPK1
MED17
MED6
MTA3
NCOR1
NCOR2
PELI1
PIN1
PML
PPARD
PRKD3
RAF1
RUNX1T1
SIAH1
SIN3A
SP1
SPI1
TRAF1
WNK4
ZBTB16
ZBTB7A
ZBTB7B
Entrez ID
23097
604
HPRD ID
07627
00180
Ensembl ID
ENSG00000155111
ENSG00000113916
Uniprot IDs
B4DUB1
Q9BWU1
B5B0A5
P41182
PDB IDs
1R28
1R29
1R2B
2EN2
2EOS
2LCE
2YRM
3BIM
3E4U
3LBZ
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Gene Expression
Gene Expression
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Gene Expression, Epigenetic
Erythrocyte Differentiation
Erythrocyte Homeostasis
Negative Regulation Of Cell Differentiation
Negative Regulation Of Cellular Metabolic Process
Myeloid Cell Homeostasis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Negative Regulation Of Cell Growth
Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Negative Regulation Of Mast Cell Cytokine Production
Negative Regulation Of Isotype Switching To IgE Isotypes
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of T-helper 2 Cell Differentiation
DNA Methylation On Cytosine Within A CG Sequence
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Homeostasis Of Number Of Cells
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Growth
Myeloid Cell Differentiation
Definitive Erythrocyte Differentiation
Aortic Smooth Muscle Cell Differentiation
Nucleocytoplasmic Transport
Nuclear Transport
RNA Metabolic Process
Glial Cell Fate Determination
Methylation-dependent Chromatin Silencing
Regulation Of Memory T Cell Differentiation
Negative Regulation Of Cellular Senescence
Negative Regulation Of Biosynthetic Process
Type 2 Immune Response
Regulation Of Cell Growth
Positive Regulation By Host Of Viral Transcription
Negative Regulation Of T-helper Cell Differentiation
Negative Regulation Of B Cell Apoptotic Process
Negative Regulation Of Cell Aging
DNA Methylation On Cytosine
Regulation Of Cell Differentiation
Histone Modification
Negative Regulation Of Alpha-beta T Cell Differentiation
Germinal Center Formation
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
RNA Metabolic Process
Negative Regulation Of Biosynthetic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Gene Expression
Macromolecule Biosynthetic Process
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Hemopoiesis
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Immune System Development
Chromatin Organization
Transcription Initiation From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Cell Differentiation
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Cell Differentiation
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Notch Signaling Pathway
Immune System Process
DNA-templated Transcription, Initiation
Response To Organic Substance
Leukocyte Differentiation
Chromatin Modification
Cellular Protein Modification Process
Developmental Process
Nitrogen Compound Metabolic Process
Organ Development
Chromosome Organization
Tagcloud
?
ablated
conducive
cor
corepressors
deacteylases
erbaalpha
erbbeta
interactiondomains
laz3
locks
mad
mxi
physicalassociation
rev
rid
rids
rip13a
rip13delta1
rpd3
rvr
sin3
sin3a
sin3b
tafii32
tafii70
tafs
terminalrepression
tfiib
zip
Tagcloud (Difference)
?
ablated
conducive
cor
corepressors
deacteylases
erbaalpha
erbbeta
interactiondomains
laz3
locks
mad
mxi
physicalassociation
rev
rid
rids
rip13a
rip13delta1
rpd3
rvr
sin3
sin3a
sin3b
tafii32
tafii70
tafs
terminalrepression
tfiib
zip
Tagcloud (Intersection)
?