TRIM35 and ANTXR1

Number of citations of the paper that reports this interaction (PubMedID 34285210)
58

Data Source:
BioGRID (two hybrid)

		TRIM35	ANTXR1
Description		tripartite motif containing 35	ANTXR cell adhesion molecule 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane Lamellipodium Membrane Filopodium Membrane Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Transmembrane Signaling Receptor Activity Protein Binding Collagen Binding Signaling Receptor Activity Metal Ion Binding Actin Filament Binding
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Suppression Of Viral Release By Host Innate Immune Response Negative Regulation Of Mitotic Cell Cycle	Blood Vessel Development Epidermal Growth Factor Receptor Signaling Pathway Actin Cytoskeleton Organization Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Assembly
Pathways		Interferon gamma signaling
Drugs			MDX-1303
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)	Alzheimer's disease ( 30636644) Appendicular lean mass ( 33097823) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673) Height ( 21998595 31562340) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29235454 29617998 29785010 30054594 31959993) Orofacial cleft x maternal periconceptional multivitamin use interaction (1df) ( 33937227) Periodontitis (stage III/IV grade C) ( 33745150)
Interacting Genes		50 interacting genes: ADIPOQ ANTXR1 BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410	10 interacting genes: ASB10 BCL2L1 BRCA1 DTX3L HDAC2 LRP6 RBCK1 RNF182 TRIM35 TRIM51
Entrez ID		23087	84168
HPRD ID		15553	05913
Ensembl ID		ENSG00000104228	ENSG00000169604
Uniprot IDs		E5RGB3 Q9UPQ4	H0YC24 Q53FL1 Q96EC6 Q9H6X2
PDB IDs			3N2N 6ADL 6ADM 6ADR 6CX1
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein Polyubiquitination Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin Protein Ligase Activity Transferase Activity Host-mediated Suppression Of Symbiont Invasion Protein Metabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Host-mediated Perturbation Of Symbiont Process Macromolecule Metabolic Process Modulation Of Process Of Another Organism Protein Binding Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process	Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Modification Process Response To Alcohol Ubiquitin-protein Transferase Activity Response To External Biotic Stimulus Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cell Cycle Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Other Organism Zinc Ion Binding Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Defense Response Response To Stress Apoptotic Process In Bone Marrow Cell Defense Response To Virus Protein Polyubiquitination Positive Regulation Of Male Mating Behavior Histone H4K91 Ubiquitin Ligase Activity Protein Autoubiquitination Cellular Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cell Cycle Negative Regulation Of Apoptotic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Protein De-2-hydroxyisobutyrylase Activity Response To Alkaloid Response To Virus Regulation Of Apoptotic Signaling Pathway Enzyme Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Damage Checkpoint Signaling Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Transferase Activity
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