TRIM35 and TRIM10

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TRIM35	TRIM10
Description		tripartite motif containing 35	tripartite motif containing 10
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Suppression Of Viral Release By Host Innate Immune Response Negative Regulation Of Mitotic Cell Cycle	Erythrocyte Differentiation Innate Immune Response Host-mediated Suppression Of Symbiont Invasion
Pathways		Interferon gamma signaling	Interferon gamma signaling
Drugs
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)	Anger ( 24489884) Autism spectrum disorder or schizophrenia ( 28540026) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) HIV-1 control ( 20041166) Immature fraction of reticulocytes ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Neuroticism ( 29255261) Red cell distribution width ( 27863252 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494) Tonsillitis ( 30037793)
Interacting Genes		50 interacting genes: ADIPOQ ANTXR1 BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410	19 interacting genes: CDK2 GEM HGS LNX1 PRKAB2 PSMA1 SCNM1 STING1 TRIM35 TRIM44 TTC23 UBE2D1 UBE2D2 UBE2D3 UBE2D4 YPEL3 ZNF148 ZNF414 ZNF620
Entrez ID		23087	10107
HPRD ID		15553	05752
Ensembl ID		ENSG00000104228	ENSG00000204613
Uniprot IDs		E5RGB3 Q9UPQ4	A0A1U9X8M5 Q9UDY6
PDB IDs			7QS0
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein Polyubiquitination Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin Protein Ligase Activity Transferase Activity Host-mediated Suppression Of Symbiont Invasion Protein Metabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Host-mediated Perturbation Of Symbiont Process Macromolecule Metabolic Process Modulation Of Process Of Another Organism Protein Binding Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process	Ubiquitin Conjugating Enzyme Activity Ubiquitin Protein Ligase Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein K6-linked Ubiquitination Regulation Of Protein Polyubiquitination Catabolic Process Zinc Ion Binding Positive Regulation Of Defense Response To Virus By Host Macromolecule Catabolic Process Protein K11-linked Ubiquitination Regulation Of Defense Response To Virus By Host Cyclic-di-GMP Binding STING Complex Protein Modification Process Nucleus Proteolysis Nucleotide Binding Y Chromosome Positive Regulation Of Heterochromatin Formation Transferase Activity Metal Ion Binding Cyclin A1-CDK2 Complex Cyclin E2-CDK2 Complex Positive Regulation Of DNA-templated DNA Replication Initiation Regulation Of Defense Response To Virus Positive Regulation Of Cytokine-mediated Signaling Pathway Negative Regulation Of Protein K48-linked Ubiquitination 2',3'-cyclic GMP-AMP Binding Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Protein Autoubiquitination Positive Regulation Of Chromatin Organization Cyclin-dependent Protein Kinase Activity Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex ESCRT-0 Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?