TRIM35 and IGFN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIM35	IGFN1
Description		tripartite motif containing 35	immunoglobulin like and fibronectin type III domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Z Disc
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Apoptotic Process Protein Ubiquitination Positive Regulation Of Apoptotic Process Suppression Of Viral Release By Host Innate Immune Response Negative Regulation Of Mitotic Cell Cycle
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Chronotype ( 30696823) Crohn's disease ( 26192919) Inflammatory bowel disease ( 26192919) Lung cancer ( 28604730)	Asthma ( 29273806) Height ( 28552196)
Interacting Genes		50 interacting genes: ADIPOQ ANTXR1 BANP CABP2 COL8A1 DTX2 ENKD1 FNDC3B GNMT HNRNPA2B1 IGFN1 KANK2 LCK LMO1 MGAT5B NRF1 PAN2 PARD6B PDCD5 PHF24 PKM PPP2CA PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QARS1 SHC3 SMARCB1 TCEANC TRAPPC6A TRIM10 TRIM11 TRIM5 TRIM55 TRIM63 TSG101 TSSK3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2K UBE2U UBE2W USP2 USP49 ZNF410	40 interacting genes: ACTMAP BANP BLZF1 COG6 CRX DDAH2 FXR2 GOLGA2 HIVEP1 HOXA1 HOXD3 KCTD9 KIFC3 KRT39 KRTAP6-2 LHX9 LZTS2 MEOX2 MID2 MYOD1 NHLRC4 PIBF1 PNMA1 POF1B POU6F2 PRKAR1B PRR23B SERTAD2 SPAG5 TAX1BP1 TRIM21 TRIM27 TRIM35 TRIM42 TRIP13 TSC1 UBAP2 USP54 ZNF620 ZNF688
Entrez ID		23087	91156
HPRD ID		15553	16812
Ensembl ID		ENSG00000104228	ENSG00000163395
Uniprot IDs		E5RGB3 Q9UPQ4	Q86VF2
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin-protein Transferase Activity Post-translational Protein Modification Protein Polyubiquitination Protein Ubiquitination Protein Modification Process Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Ubiquitin Protein Ligase Activity Transferase Activity Host-mediated Suppression Of Symbiont Invasion Protein Metabolic Process Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Host-mediated Perturbation Of Symbiont Process Macromolecule Metabolic Process Modulation Of Process Of Another Organism Protein Binding Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process	Suppression Of Viral Release By Host Negative Regulation Of Viral Transcription Regulation Of Viral Transcription Protein Binding Golgi Organization Protein Localization To Cytoskeleton Sequence-specific Double-stranded DNA Binding
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