ANTXR1 and RNF182

Number of citations of the paper that reports this interaction (PubMedID 34285210)
58

Data Source:
BioGRID (two hybrid)

		ANTXR1	RNF182
Description		ANTXR cell adhesion molecule 1	ring finger protein 182
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Cell Surface Endosome Membrane Membrane Lamellipodium Membrane Filopodium Membrane Cell Projection	Cytoplasm Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Collagen Binding Signaling Receptor Activity Metal Ion Binding Actin Filament Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Blood Vessel Development Epidermal Growth Factor Receptor Signaling Pathway Actin Cytoskeleton Organization Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Extracellular Matrix Assembly	Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs		MDX-1303
Diseases
GWAS		Alzheimer's disease ( 30636644) Appendicular lean mass ( 33097823) Glaucoma ( 30054594) Glaucoma (primary open-angle) ( 33627673) Height ( 21998595 31562340) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29235454 29617998 29785010 30054594 31959993) Orofacial cleft x maternal periconceptional multivitamin use interaction (1df) ( 33937227) Periodontitis (stage III/IV grade C) ( 33745150)	Lymphoma ( 23349640) Mean corpuscular hemoglobin concentration ( 27863252) Metabolite levels ( 23823483)
Interacting Genes		10 interacting genes: ASB10 BCL2L1 BRCA1 DTX3L HDAC2 LRP6 RBCK1 RNF182 TRIM35 TRIM51	6 interacting genes: ANTXR1 UBC UBE2D1 UBE2K UBE2L3 UBE2N
Entrez ID		84168	221687
HPRD ID		05913	15264
Ensembl ID		ENSG00000169604	ENSG00000180537
Uniprot IDs		H0YC24 Q53FL1 Q96EC6 Q9H6X2	Q8N6D2
PDB IDs		3N2N 6ADL 6ADM 6ADR 6CX1
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Modification Process Response To Alcohol Ubiquitin-protein Transferase Activity Response To External Biotic Stimulus Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cell Cycle Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Other Organism Zinc Ion Binding Protein Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Defense Response Response To Stress Apoptotic Process In Bone Marrow Cell Defense Response To Virus Protein Polyubiquitination Positive Regulation Of Male Mating Behavior Histone H4K91 Ubiquitin Ligase Activity Protein Autoubiquitination Cellular Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Cell Cycle Negative Regulation Of Apoptotic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex Protein De-2-hydroxyisobutyrylase Activity Response To Alkaloid Response To Virus Regulation Of Apoptotic Signaling Pathway Enzyme Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Damage Checkpoint Signaling Dendritic Cell Proliferation Dendritic Cell Apoptotic Process Transferase Activity	Ubiquitin Conjugating Enzyme Activity Modification-dependent Protein Catabolic Process Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Polyubiquitination Ubiquitin Protein Ligase Binding Protein Modification Process Post-translational Protein Modification Ubiquitin-protein Transferase Activator Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Protein Ubiquitination Macromolecule Catabolic Process Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Polyubiquitination Proteolysis Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Regulation Of Protein Polyubiquitination Regulation Of Protein Modification Process Regulation Of Post-translational Protein Modification Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Transferase Activity Catabolic Process Negative Regulation Of TORC1 Signaling TORC1 Signaling Peptidyl-lysine Demalonylation Protein Demalonylation Protein Desuccinylation Peptidyl-lysine Desuccinylation Protein-malonyllysine Demalonylase Activity TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Response To Nutrient Levels Protein K48-linked Ubiquitination Protein-glutaryllysine Deglutarylase Activity Protein-succinyllysine Desuccinylase Activity Protein Deglutarylation Ubiquitin Ligase Complex ATP Binding UBC13-MMS2 Complex Regulation Of TOR Signaling Ubiquitin Conjugating Enzyme Complex Regulation Of Protein Metabolic Process Histone Deacetylase Activity, NAD-dependent Macromolecule Metabolic Process Nucleotide Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?