ERC1 and GALNT8

		ERC1	GALNT8
Description		ELKS/RAB6-interacting/CAST family member 1	polypeptide N-acetylgalactosaminyltransferase 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Podosome Cytoplasm Golgi Apparatus Centrosome Cytoskeleton Plasma Membrane IkappaB Kinase Complex Membrane Ciliary Basal Body Presynaptic Membrane Cell Projection Synapse Anchoring Junction Presynapse Presynaptic Active Zone Cytoplasmic Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding PDZ Domain Binding Small GTPase Binding Cadherin Binding Structural Constituent Of Presynaptic Active Zone	Polypeptide N-acetylgalactosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity Carbohydrate Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription I-kappaB Phosphorylation Protein Transport Retrograde Transport, Endosome To Golgi Maintenance Of Presynaptic Active Zone Structure Positive Regulation Of NF-kappaB Transcription Factor Activity	Protein Glycosylation Protein O-linked Glycosylation Protein O-linked Glycosylation Via N-acetyl-galactosamine
Pathways			O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (hyperactivity-impulsivity symptoms) ( 32595297) Body mass index ( 26426971) Femur bone mineral density x serum urate levels interaction ( 34046847) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420) Medial temporal lobe substructure volumes ( 32768867) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Gut microbiota (bacterial taxa) ( 27723756)
Interacting Genes		11 interacting genes: APP DNAJC5 DYRK1A ITSN2 PPFIA1 RAB6A RAB6B RIMS1 SRPK2 UBC YWHAG	1 interacting genes: DOLK
Entrez ID		23085	26290
HPRD ID		06181	09374
Ensembl ID		ENSG00000082805	ENSG00000130035
Uniprot IDs		G8JLD3 Q8IUD2 X6RLX0 X6RM00	Q9NY28
PDB IDs
Enriched GO Terms of Interacting Partners?		Presynapse Endosome To Plasma Membrane Transport Vesicle Protein Localization To Golgi Membrane Vesicle-mediated Transport RAGE Receptor Binding Regulation Of Neuron Apoptotic Process Astrocyte Activation Positive Regulation Of Superoxide Anion Generation Myosin V Binding Positive Regulation Of Dendrite Extension Vesicle-mediated Transport In Synapse Regulation Of Modification Of Synaptic Structure Regulation Of Modification Of Postsynaptic Structure Regulation Of Superoxide Anion Generation Positive Regulation Of Monocyte Chemotaxis Protein Localization To Golgi Apparatus Regulation Of Superoxide Metabolic Process Microglial Cell Activation Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Monocyte Chemotaxis Leukocyte Activation Involved In Inflammatory Response Synaptic Vesicle Exocytosis Intra-Golgi Vesicle-mediated Transport Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Histone H3T45 Kinase Activity Peptidyl-cysteine Methylation Protein Methylation Positive Regulation Of Vitamin D 24-hydroxylase Activity Presynaptic Active Zone Positive Chemotaxis Regulation Of Cellular Component Organization Positive Regulation Of ERK1 And ERK2 Cascade Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Modulation Of Excitatory Postsynaptic Potential	Dolichol Kinase Activity Dolichol Phosphate Mannose Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process I-kappaB Phosphorylation Structural Constituent Of Presynaptic Active Zone Maintenance Of Presynaptic Active Zone Structure IkappaB Kinase Complex Presynaptic Active Zone Organization Presynaptic Active Zone Cytoplasmic Component Isoprenoid Biosynthetic Process Maintenance Of Synapse Structure Podosome Phosphate-containing Compound Metabolic Process Cell Junction Maintenance Glycolipid Biosynthetic Process Cellular Component Maintenance Protein N-linked Glycosylation PDZ Domain Binding Positive Regulation Of NF-kappaB Transcription Factor Activity Glycolipid Metabolic Process Terpenoid Metabolic Process Isoprenoid Metabolic Process Retrograde Transport, Endosome To Golgi
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