FNBP1 and SNX2

Number of citations of the paper that reports this interaction (PMID 11438682)
17

Data Source:
HPRD (two hybrid, in vivo)

		FNBP1	SNX2
Gene Name		formin binding protein 1	sorting nexin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Cytoskeleton Plasma Membrane Coated Pit Cell Cortex Cytoplasmic Membrane-bounded Vesicle	Cytoplasm Endosome Membrane Membrane Extrinsic Component Of Membrane Lamellipodium Retromer Complex Early Endosome Membrane Intracellular Membrane-bounded Organelle Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Phosphatidylinositol Binding Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process	Endocytosis	Intracellular Protein Transport Endocytosis Vesicle Organization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Protein Oligomerization Lamellipodium Morphogenesis
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AKAP9 ARHGAP17 CBL CDC42 DNM1 DNM2 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL	20 interactors: ACVR1B ACVR2B C1orf122 CSNK2B DUSP10 EGFR FNBP1 INSR LAMC1 LEPR MET NFYC PAK6 PDGFRA PDGFRB SNX1 SNX4 SNX5 SNX6 ZNF202
Entrez ID		23048	6643
HPRD ID		10446	09332
Ensembl ID		ENSG00000187239	ENSG00000205302
Uniprot IDs		B7ZL12 B7ZL13 B7ZL14 Q96RU3	B4DEK4 B7Z408 O60749
PDB IDs		2EFL
Enriched GO Terms of Interacting Partners?		Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Signal Transduction Ephrin Receptor Signaling Pathway Negative Regulation Of Membrane Tubulation Signaling Cell Communication Endocytosis Cellular Response To Stimulus Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Neuron Projection Morphogenesis Cell Projection Organization Cell Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Organelle Localization Response To Stimulus Positive Regulation Of Signal Transduction Axon Guidance Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Organelle Localization Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of ERBB Signaling Pathway Cell-cell Signaling Generation Of Neurons Regulation Of Catalytic Activity Neuron Development Regulation Of Cell Projection Organization Nitric Oxide Metabolic Process Anatomical Structure Morphogenesis Cell Differentiation Positive Regulation Of Metabolic Process Neurogenesis Reactive Nitrogen Species Metabolic Process Endosome Organization Axonogenesis Positive Regulation Of Cellular Metabolic Process Establishment Of Vesicle Localization Regulation Of Intracellular Signal Transduction Vesicle Localization Positive Regulation Of Receptor-mediated Endocytosis Axon Development Regulation Of Nitric-oxide Synthase Activity Anatomical Structure Development Response To External Stimulus	Regulation Of Kinase Activity Protein Autophosphorylation Regulation Of Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Signal Transduction By Phosphorylation Positive Regulation Of Phosphorylation Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Regulation Of Cell Migration Positive Regulation Of Locomotion Protein Phosphorylation Regulation Of Cell Motility Phosphorylation Regulation Of Signaling Retina Vasculature Development In Camera-type Eye Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Metanephric Glomerular Capillary Formation Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Peptidyl-tyrosine Phosphorylation Tissue Development Positive Regulation Of Signal Transduction Regulation Of MAP Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Regulation Of Catalytic Activity Chemotaxis Positive Regulation Of DNA Metabolic Process Digestive System Development Regulation Of MAPK Cascade Regulation Of Cellular Protein Metabolic Process Glomerular Capillary Formation Positive Regulation Of Phospholipase C Activity Positive Regulation Of Cellular Protein Metabolic Process Retrograde Transport, Endosome To Golgi Tube Morphogenesis Endosomal Transport Metanephric Glomerulus Vasculature Development Digestive Tract Morphogenesis
Tagcloud ?		11p 12p 17q11 6q16 9p21 9q34 af10 c9orf78 calm concurring cryptic del grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20	assembles assembling autonomously cation comprises conflicting endosomal endosomes heterodimer heterotrimer homodimer interchangeable mammalian mannose named nexin obligate performing retrieval retromer retromers snx1 sorting subcomplexes tgn truly vps26 vps29 vps35
Tagcloud (Difference) ?		11p 12p 17q11 6q16 9p21 9q34 af10 c9orf78 calm concurring cryptic del grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20	assembles assembling autonomously cation comprises conflicting endosomal endosomes heterodimer heterotrimer homodimer interchangeable mammalian mannose named nexin obligate performing retrieval retromer retromers snx1 sorting subcomplexes tgn truly vps26 vps29 vps35
Tagcloud (Intersection) ?