ABCF3 and LAMTOR1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ABCF3	LAMTOR1
Gene Name		ATP-binding cassette, sub-family F (GCN20), member 3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane	Lysosome Lysosomal Membrane Golgi Apparatus Plasma Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Vesicular Exosome Ragulator Complex
	Molecular Function	ATP Binding ATPase Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process	Metabolic Process Defense Response To Virus	Regulation Of Receptor Recycling Endosome Organization Lysosome Organization Regulation Of Cholesterol Esterification Regulation Of Cholesterol Efflux Cell Growth Positive Regulation Of TOR Signaling Lysosome Localization Endosome Localization Cellular Protein Localization Cholesterol Homeostasis Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Regulation Of Cholesterol Import Cellular Response To Amino Acid Stimulus
Pathways
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		14 interactors: ACIN1 CCDC33 DLEU1 DNALI1 FCHSD2 HIRIP3 LAMTOR1 MOCS2 NOA1 SLC35E1 SPP1 TBPL1 TOE1 TRIM27	4 interactors: ABCF3 CAPN1 CCDC90B EEF1A1
Entrez ID		55324	55004
HPRD ID		12404	07933
Ensembl ID		ENSG00000161204	ENSG00000149357
Uniprot IDs		Q9NUQ8	F5H479 Q6IAA8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Reproduction Organelle Organization Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Interleukin-2 Secretion Single Organism Reproductive Process Endosome Localization Regulation Of Cholesterol Import Reproductive Process DTTP Biosynthetic Process Apoptotic Chromosome Condensation Negative Regulation Of Calcium Ion Import Positive Regulation Of Monocyte Differentiation Negative Regulation Of Collateral Sprouting
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