ABCF3 and MOCS2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ABCF3	MOCS2
Gene Name		ATP-binding cassette, sub-family F (GCN20), member 3	molybdenum cofactor synthesis 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane	Nucleus Cytoplasm Cytosol Molybdopterin Synthase Complex Extracellular Vesicular Exosome
	Molecular Function	ATP Binding ATPase Activity	Nucleotide Binding Molybdopterin Synthase Activity Identical Protein Binding
	Biological Process	Metabolic Process Defense Response To Virus	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Biosynthetic Process Small Molecule Metabolic Process
Pathways			Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Molybdenum cofactor biosynthesis Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Molybdenum cofactor biosynthesis Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS		Major depressive disorder ( 22472876)
Protein-Protein Interactions		14 interactors: ACIN1 CCDC33 DLEU1 DNALI1 FCHSD2 HIRIP3 LAMTOR1 MOCS2 NOA1 SLC35E1 SPP1 TBPL1 TOE1 TRIM27	3 interactors: ABCF3 MOCS3 RPL9
Entrez ID		55324	4338
HPRD ID		12404	04750
Ensembl ID		ENSG00000161204	ENSG00000164172
Uniprot IDs		Q9NUQ8	O96007 O96033
PDB IDs			4AP8
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Reproduction Organelle Organization Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Interleukin-2 Secretion Single Organism Reproductive Process Endosome Localization Regulation Of Cholesterol Import Reproductive Process DTTP Biosynthetic Process Apoptotic Chromosome Condensation Negative Regulation Of Calcium Ion Import Positive Regulation Of Monocyte Differentiation Negative Regulation Of Collateral Sprouting	TRNA Wobble Position Uridine Thiolation Enzyme Active Site Formation Via L-cysteine Persulfide Protein Adenylylation Protein Urmylation TRNA Thio-modification TRNA Wobble Uridine Modification Molybdopterin Cofactor Biosynthetic Process Molybdopterin Cofactor Metabolic Process Mo-molybdopterin Cofactor Biosynthetic Process
Tagcloud ?			1136a 667inscga aldehyde brazilian catabolism cofactor confirmation deficiencies deterioration detoxification encephalopathy geph homocysteine inborn mocs1 mocs3 molybdenum obtaining oxidase radiologic resembling specialized sulfite sulfur suox tentative turkish uric xanthine
Tagcloud (Difference) ?			1136a 667inscga aldehyde brazilian catabolism cofactor confirmation deficiencies deterioration detoxification encephalopathy geph homocysteine inborn mocs1 mocs3 molybdenum obtaining oxidase radiologic resembling specialized sulfite sulfur suox tentative turkish uric xanthine
Tagcloud (Intersection) ?