EIF5 and NRGN

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EIF5	NRGN
Gene Name		eukaryotic translation initiation factor 5	neurogranin (protein kinase C substrate, RC3)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane	Intracellular
	Molecular Function	Translation Initiation Factor Activity GTPase Activity GTP Binding Translation Factor Activity, Nucleic Acid Binding Poly(A) RNA Binding	Calmodulin Binding
	Biological Process	Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Cellular Protein Metabolic Process	Signal Transduction Nervous System Development Intracellular Signal Transduction
Pathways		Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Translation Eukaryotic Translation Initiation Cap-dependent Translation Initiation
Drugs
Diseases
GWAS		Red blood cell traits ( 23222517)	Schizophrenia ( 19571808)
Protein-Protein Interactions		14 interactors: APP CSNK2A1 CSNK2B DUSP12 EIF1AX EIF1AY EIF2S2 EIF3D EIF3G EIF4G1 EIF4G2 NCBP2 NRGN PUM1	6 interactors: CALM1 EIF5 GLP1R PRKCA PRKCB PRKCG
Entrez ID		1983	4900
HPRD ID		03417	03828
Ensembl ID		ENSG00000100664	ENSG00000154146
Uniprot IDs		P55010 Q6IBU0	Q92686
PDB IDs		2E9H 2G2K 2IU1
Enriched GO Terms of Interacting Partners?		Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Posttranscriptional Regulation Of Gene Expression Translation Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Protein Metabolic Process Gene Expression MRNA 3'-end Processing Protein Metabolic Process RNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Formation Of Translation Preinitiation Complex Ribonucleoprotein Complex Assembly Cellular Macromolecular Complex Assembly Biosynthetic Process Ribonucleoprotein Complex Biogenesis Cellular Metabolic Process SnRNA Export From Nucleus Positive Regulation Of RNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Formation Of Cytoplasmic Translation Initiation Complex Axon Guidance Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Processing Collateral Sprouting In Absence Of Injury Cytokine-mediated Signaling Pathway Male Germ Cell Proliferation Regulation Of Metabolic Process Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Axonogenesis Cellular Component Assembly Nuclear-transcribed MRNA Catabolic Process MRNA Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis MRNA Catabolic Process Axon Choice Point Recognition Axon Development RNA Processing Cellular Response To Cytokine Stimulus Cell Morphogenesis Involved In Neuron Differentiation Cytoplasmic Translational Initiation Positive Regulation Of Glucokinase Activity Positive Regulation Of Activin Receptor Signaling Pathway Chemotaxis Adiponectin-activated Signaling Pathway	Activation Of Adenylate Cyclase Activity Histone H3-T6 Phosphorylation Positive Regulation Of Adenylate Cyclase Activity Platelet Activation Positive Regulation Of Lyase Activity Activation Of Phospholipase C Activity Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Phospholipase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of Phospholipase Activity Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Regulation Of CAMP Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Energy Reserve Metabolic Process Regulation Of Body Fluid Levels Synaptic Transmission Wound Healing Negative Regulation Of Glucose Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Fibroblast Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Cell Activation Response To Fibroblast Growth Factor Response To Wounding Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Intracellular Signal Transduction Cellular Response To Organic Substance Rhodopsin Mediated Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell-cell Signaling Mitotic Nuclear Envelope Disassembly Cellular Calcium Ion Homeostasis Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Insulin Receptor Signaling Pathway Calcium Ion Homeostasis Histone Phosphorylation Nuclear Envelope Disassembly Peptidyl-threonine Phosphorylation
Tagcloud ?		40s 429c cdna cdnas cloning deduced eif3 encodes eukaryotic frame homogeneity identity incorporated initiator laboratories lysates methionyl mr35 multisubunit p42 polyhistidine reading similarity tagged tif35p transiently trna u20s ydr
Tagcloud (Difference) ?		40s 429c cdna cdnas cloning deduced eif3 encodes eukaryotic frame homogeneity identity incorporated initiator laboratories lysates methionyl mr35 multisubunit p42 polyhistidine reading similarity tagged tif35p transiently trna u20s ydr
Tagcloud (Intersection) ?